| Prevalence of hematological abnormalities in patients with Sheehan's syndrome: response to replacement of glucocorticoids and thyroxine. | |
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MedLine Citation:
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PMID: 20798990 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Anemia and other hematological abnormalities are common in patients with Sheehan's syndrome. The response of these abnormalities to replacement of thyroxine and glucocorticoids is not clear. The aim of the present study was to document the profile of hematological abnormalities and response to treatment in patients with Sheehan's syndrome. Forty patients of Sheehan's syndrome and an equal number of age and parity matched healthy controls were studied for prevalence of hematological abnormalities. Hemoglobin concentration, hematocrit, red cell, white cell and platelet count were significantly decreased in patients with Sheehan's syndrome compared to controls. Frequency of anemia, leucopenia, thrombocytopenia and pancytopenia was significantly higher in these patients compared to controls. After achieving euthyroid and eucortisol state, there was a complete recovery of these hematological abnormalities. We conclude that anemia and other cytopenias are common in patients with Sheehan's syndrome and replacement with thyroxine and glucocorticoids results in complete recovery of these abnormalities. |
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Authors:
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Bashir Ahmad Laway; Shahnaz Ahmad Mir; Mir Iftikhar Bashir; Javid Rasool Bhat; Jeelani Samoon; Abdul Hamid Zargar |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pituitary Volume: 14 ISSN: 1573-7403 ISO Abbreviation: Pituitary Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9814578 Medline TA: Pituitary Country: United States |
Other Details:
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Languages: eng Pagination: 39-43 Citation Subset: IM |
Affiliation:
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Department of Endocrinology, Sher-I- Kashmir Institute of Medical Sciences Soura, Srinagar, Jammu and Kashmir, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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