Document Detail

Prevalence of hand symptoms, impairments and activity limitations in rheumatoid arthritis in relation to disease duration.
MedLine Citation:
PMID:  21031287     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the prevalence of hand and wrist symptoms and impairments, and the resulting activity limitations in relation to disease duration in patients with rheumatoid arthritis.
DESIGN AND PATIENTS: A cross-sectional study included 200 consecutive patients with rheumatoid arthritis in 4 categories of disease duration: 2-4, 4-6, 6-8 and ≥ 8 years. Patients were asked about the presence of various hand and wrist symptoms, and underwent a standardized physical examination. To evaluate activity limitations, patients completed the Disabilities of the Arm Shoulder and Hand questionnaire and scored their limitations on a Numerical Rating Scale (0 = no to 10 = maximum limitation).
RESULTS: Of all patients, 94% suffered from at least one symptom, and 67% had at least one impairment, mostly from the earliest stages onwards. The median standardized Disabilities of the Arm Shoulder and Hand score (interquartile range) was 26.7 (10.8-42.5). The mean Numerical Rating Scale score for activity limitations was 2.99 (standard deviation 2.50) in the dominant hand and 2.59 (standard deviation 2.49) in the non-dominant hand.
CONCLUSION: A high prevalence of hand and wrist symptoms and impairments is often already present after 2 years of disease duration. We recommend that physicians specifically screen for these symptoms and impairments, starting 2 years after the diagnosis of rheumatoid arthritis.
Noortje C A Horsten; Jennie Ursum; Leo D Roorda; Dirkjan van Schaardenburg; Joost Dekker; Agnes F Hoeksma
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of rehabilitation medicine     Volume:  42     ISSN:  1651-2081     ISO Abbreviation:  J Rehabil Med     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-29     Completed Date:  2010-11-12     Revised Date:  2014-05-30    
Medline Journal Info:
Nlm Unique ID:  101088169     Medline TA:  J Rehabil Med     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  916-21     Citation Subset:  IM    
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MeSH Terms
Activities of Daily Living
Arthritis, Rheumatoid / diagnosis,  physiopathology*
Cohort Studies
Cross-Sectional Studies
Disability Evaluation
Hand / physiopathology*
Hand Strength / physiology
Longitudinal Studies
Middle Aged
Range of Motion, Articular / physiology
Time Factors
Wrist Joint / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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