Document Detail


Prevalence of glucose-6-phosphate dehydrogenase deficiency in Northern Greece.
MedLine Citation:
PMID:  18290815     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Glucose-6-phosphate dehydrogenase (G6PD) deficiency affects more than 400 million persons worldwide. Its distribution varies significantly among different geographic regions and different population groups. Purpose of our study was to estimate its prevalence in Northern Greece. The dataset comprised 5161 newborns and adults who were screened for G6PD deficiency between July 2001 and March 2007. G6PD deficiency was detected by the dye reduction method. In the screened group, 6.3% of subjects were G6PD deficient. Moderate enzyme deficiency was shown in 139 individuals (2.7%). Complete deficiency was identified in 3.7%. The prevalence of G6PD deficiency in Northern Greece is much higher compared with the general Greek population. Moreover, G6PD prevalence in the male sex is much higher - almost double - that in the female sex.
Authors:
G Ntaios; A Chatzinikolaou; C Tomos; C Manolopoulos; P Karalazou; A Nikolaidou; S Alexiou-Daniel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Internal medicine journal     Volume:  38     ISSN:  1445-5994     ISO Abbreviation:  Intern Med J     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-22     Completed Date:  2008-03-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092952     Medline TA:  Intern Med J     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  204-6     Citation Subset:  IM    
Affiliation:
First Propedeutic Department of Internal Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. ntaiosgeorge@yahoo.gr
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Glucosephosphate Dehydrogenase Deficiency / epidemiology*
Greece / epidemiology
Humans
Male
Prevalence

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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