Document Detail


Prevalence of gestational exposure to cannabis in a Mediterranean city by meconium analysis.
MedLine Citation:
PMID:  17953730     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To investigate the prevalence of in utero exposure to cannabis in a cohort of 974 mother-infants dyads from Barcelona (Spain). METHODS: A validated gas chromatographic-mass spectrometric assay was used for meconium analysis. RESULTS: Prenatal exposure to cannabis was detected in 5.3% newborns; however, only 1.7% of the participating mothers disclosed gestational drug use. Ethnicity was not associated with cannabis use, nor were the maternal features or newborns somatometry. A significantly higher percentage of cannabis using mothers had a managerial professional job versus nonusers. CONCLUSIONS: Meconium analysis is especially important to identify neonates who have been exposed to cannabis in utero, which appear normal at birth and therefore may not be recognized. Timely detection of these newborns at risk provides the basis for appropriate treatment and adequate medical and social follow-up.
Authors:
Jaime Lozano; Oscar García-Algar; Emilia Marchei; Oriol Vall; Toni Monleon; Rita Di Giovannandrea; Simona Pichini
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-10-22
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  96     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-16     Completed Date:  2008-02-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1734-7     Citation Subset:  IM    
Affiliation:
Unitat de Recerca Infància i Entorn (URIE), Paediatric Service, Hospital del Mar, and Departament de Pediatria, Ginecologia i Obstetrica, i Medicina Preventiva, Universitat Autònoma, Barcelona, Spain.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Biological Markers / chemistry
Cannabinoids / analysis*
Cannabis*
Cohort Studies
Female
Gas Chromatography-Mass Spectrometry
Humans
Infant, Newborn
Male
Marijuana Abuse / epidemiology*
Maternal Exposure*
Meconium / chemistry*
Pregnancy
Pregnancy Complications / epidemiology*
Prevalence
Questionnaires
Risk Factors
Socioeconomic Factors
Spain / epidemiology
Substance Abuse Detection / methods
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Cannabinoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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