Document Detail


Prevalence of gastric varices and portal hypertensive gastropathy in patients with Symmers periportal fibrosis.
MedLine Citation:
PMID:  18299649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND OBJECTIVE: Symmers periportal fibrosis secondary to schistosomiasis is a common cause of portal hypertension worldwide. Data on the prevalence of gastric varices and portal hypertensive gastropathy in this group of patients with portal hypertension is relatively scarce. The aim of this study was to determine the prevalence of gastric varices and portal hypertensive gastropathy in patients presenting with portal hypertension secondary to Symmers periportal fibrosis. PATIENTS AND METHODS: In a prospective study, upper gastrointestinal endoscopy was carried out to determine the prevalence of gastric varices and portal hypertensive gastropathy in patients with portal hypertension secondary to Symmers periportal fibrosis. RESULTS: Of 143 patients studied, 24 patients (16.8%) had gastric varices (grade I in 10.5%, grade II in 6.3%) and 31 patients (21.7%) had portal hypertensive gastropathy (mild in 11.2%, severe in 10.5%). Gastric varices were more prevalent in patients with grade I and II esophageal varices and portal hypertensive gastropathy was more prevalent in those with grade III and IV esophageal varices, but the differences were not statistically significant. CONCLUSION: We concluded that both gastric varices and portal hypertensive gastropathy seem to have a lower prevalence in patients with portal hypertension secondary to Symmers periportal fibrosis when compared to reported data in patients with portal hypertension secondary to liver cirrhosis and non-cirrhotic portal fibrosis.
Authors:
Hatim Mudawi; Yasir Ali; Mohamed El Tahir
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Annals of Saudi medicine     Volume:  28     ISSN:  0256-4947     ISO Abbreviation:  Ann Saudi Med     Publication Date:    2008 Jan-Feb
Date Detail:
Created Date:  2008-02-26     Completed Date:  2008-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8507355     Medline TA:  Ann Saudi Med     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  42-4     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Faculty of Medicine University of Khartoum, Khartoum, Sudan. hmudawi@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Animals
Endoscopy
Esophageal and Gastric Varices / diagnosis,  epidemiology*,  etiology
Female
Gastritis / diagnosis,  epidemiology*,  etiology
Humans
Hypertension, Portal / diagnosis,  epidemiology*,  etiology
Male
Middle Aged
Portal Vein / parasitology,  pathology,  ultrasonography
Prevalence
Prospective Studies
Schistosoma mansoni / isolation & purification
Schistosomiasis mansoni / complications*,  diagnosis,  epidemiology
Severity of Illness Index
Splenic Vein / parasitology,  pathology,  ultrasonography
Sudan / epidemiology

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