Document Detail


Prevalence of the fragile X syndrome in an institution for the mentally handicapped.
MedLine Citation:
PMID:  3779244     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In an investigation to find the prevalence of the fragile X (Martin Bell) syndrome in a mental handicap hospital, chromosomal investigations were carried out in 196 males selected out of a total of 512, and also in 20 female patients who were related to some of the selected males. Fragile X cells were found in 41 of the males and two of the females; in 21 of the males it was associated with macro-orchidism. The overall prevalence in the hospital for males (8.0%) ranks this syndrome next in importance to Down's syndrome as a known cause for mental handicap.
Authors:
D A Primrose; R el-Matmati; E Boyd; C Gosden; M Newton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of psychiatry : the journal of mental science     Volume:  148     ISSN:  0007-1250     ISO Abbreviation:  Br J Psychiatry     Publication Date:  1986 Jun 
Date Detail:
Created Date:  1986-12-29     Completed Date:  1986-12-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0342367     Medline TA:  Br J Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  655-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fragile X Syndrome / complications,  epidemiology*,  pathology
Hospitals, Psychiatric
Humans
Intelligence
Male
Sex Chromosome Aberrations / epidemiology*
Testicular Diseases / complications
Testis / pathology

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