| Prevalence and extent of right-to-left shunt in migraine: a survey of 217 Chinese patients. | |
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MedLine Citation:
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PMID: 22747847 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Recently, contrast-enhanced transcranial Doppler (cTCD) studies have shown that right-to-left shunt (RLS) may be a risk factor for migraine in Westerners; however, limited data in the literature describes the prevalence of RLS in Chinese patients with migraine. OBJECTIVE: To assess the prevalence of RLS in patients with migraine in China and to evaluate the relationship between the extent of RLS and migraine. METHODS: A total of 217 consecutive patients with a diagnosis of migraine and 100 volunteers were recruited. cTCD was used to assess the prevalence and the extent of RLS in all subjects. RESULTS: In the migraine group, the rate of positive RLS was 44.2% (96/217), with 23.5% (51/217) of these being large. In the healthy group, 28.0% (28/100) were positive for RLS overall, and 5.0% (5/100) were large (P = 0.006; P < 0.001). In patients having migraines with aura (MwA), 66.1% (39/59) were positive for RLS overall, and 37.3% (22/59) were large, which was significantly higher when compared with the healthy group (P < 0.001; P < 0.001); in patients having migraines without aura (MwoA), 36.1% (57/158) were positive for RLS overall, and 18.4% (29/158) were large, which was against significantly higher (P < 0.001; P = 0.003). In the MwoA group, the large RLS rate was also higher than in the healthy group (P = 0.002). CONCLUSIONS: A close correlation has been documented between RLS and migraine, especially MwA, but these relationships exist only when the shunts were large. |
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Authors:
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Y Yang; Z-N Guo; J Wu; H Jin; X Wang; J Xu; J Feng; Y Xing |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-30 |
Journal Detail:
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Title: European journal of neurology : the official journal of the European Federation of Neurological Societies Volume: - ISSN: 1468-1331 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-7-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9506311 Medline TA: Eur J Neurol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Author(s) European Journal of Neurology © 2012 EFNS. |
Affiliation:
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Department of Neurology, The First Norman Bethune Hospital of Jilin University, Chang Chun, China. |
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