Document Detail

Prevalence of equine polysaccharide storage myopathy and other myopathies in two equine populations in the United Kingdom.
MedLine Citation:
PMID:  18375158     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to determine the prevalence of equine polysaccharide storage myopathy (EPSM) in two populations of horses in the UK. Biopsy specimens from 94 horses presented to an abattoir (population 1), and 46 horses with neuromuscular disorders presented to a university referral hospital (population 2) were obtained over a period of 4years. Histological sections were examined by a veterinary pathologist for lesions including abnormal polysaccharide inclusions in myofibres. In population 1, a diagnosis of EPSM was made in 8% and non-specific myopathy in 33% of horses. In population 2, a diagnosis of EPSM was made in 22%, equine motor neurone disease (EMND) in 15% and non-specific myopathy in 37%. Within each population there was no difference in age, sex or breed distribution and muscle disease diagnosis. However, populations differed from each other in age and breed distributions and muscle disease diagnosis. EPSM was found in draft, Warmblood and related breeds and was diagnosed for the first time in cob-types. EMND was reported in 7/46 horses presented for neuromuscular disease and weakness, representing an important diagnosis in the UK. This study showed a high prevalence of EPSM and other myopathies in typical breeds of horses in the UK.
C M McGowan; T W McGowan; J C Patterson-Kane
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Publication Detail:
Type:  Journal Article     Date:  2008-03-28
Journal Detail:
Title:  Veterinary journal (London, England : 1997)     Volume:  180     ISSN:  1090-0233     ISO Abbreviation:  Vet. J.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-03-17     Completed Date:  2009-06-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706281     Medline TA:  Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  330-6     Citation Subset:  IM    
Department of Equine and Small Animal Medicine, The University of Helsinki, P.O. Box 57, 00014, Helsinki, Finland.
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MeSH Terms
Great Britain / epidemiology
Horse Diseases / epidemiology*
Muscular Diseases / epidemiology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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