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Prevalence of electrocardiographic left ventricular hypertrophy in human hypertension: an updated review.
MedLine Citation:
PMID:  22914541     Owner:  NLM     Status:  Publisher    
AIM:: Left ventricular hypertrophy (LVH) is a strong predictor of cardiovascular events in different clinical settings. We reviewed recent studies on the prevalence of hypertensive LVH, as assessed by ECG, in order to update our knowledge about this marker of cardiac organ damage in human hypertension. DESIGN:: A MEDLINE search using the key words ' LVH ', 'hypertension', 'ECG', 'cardiac organ damage' and 'cardiac hypertrophy' was performed in order to identify relevant articles. Full articles published in English language in the last decade (1 January 2000 to 31 December 2010) reporting studies in adult or elderly individuals, were considered. RESULTS:: A total of 26 studies, including 40 444 untreated and treated individuals (85% whites, 47% men, 32% obese, 28% diabetics and 22% patients with cardiovascular disease) were considered. LVH was defined by 15 criteria (seven studies used two or more criteria, range 2-7); LVH prevalence consistently varied among studies (0.6-40.0%) with an average of 18% in the pooled population. A sex-based analysis in five out of 26 studies (12 084 patients) showed an average prevalence of LVH of 24% in men and 16% in women (odds ratio 1.38, 95% CI 0.91-2.09, P = 0.11). CONCLUSION:: Our analysis shows that LVH, as assessed by ECG, is present in a relevant fraction of the hypertensive population; these data highlight the role of ECG as a first-line examination for identifying subclinical organ damage and optimizing blood pressure control in hypertensive patients.
Cesare Cuspidi; Marta Rescaldani; Carla Sala; Francesca Negri; Guido Grassi; Giuseppe Mancia
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-18
Journal Detail:
Title:  Journal of hypertension     Volume:  -     ISSN:  1473-5598     ISO Abbreviation:  J. Hypertens.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
aDepartment of Clinical Medicine and Prevention, University of Milano-Bicocca bIstituto Auxologico Italiano, Milano cDepartment of Clinical Sciences and Community Health, University of Milano and, Fondazione Policlinico di Milano dCentro Interuniversitario di Fisiologia Clinica e Ipertensione, University of Milano eIRCCS Istituto di Ricerca a Carattere Scientifico Multimedica, Sesto San Giovanni, Milano, Italy.
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