| Prevalence of dyslipidaemia in apparently healthy professionals in Asaba, South South Nigeria. | |
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MedLine Citation:
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PMID: 19320405 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Hypercholesterolaemia is a major risk factor for coronary heart disease (CHD) especially in industrialized societies. Coronary heart disease is becoming an increasing cause of death even in the developing world. OBJECTIVE: To determine the prevalence of dyslipidaemia in apparently healthy professionals in a developing economy. METHOD: One hundred apparently healthy professionals were recruited from several professions by stratified random sampling. This population was believed to be at higher risk of dyslipidaemia considering their more likely "western diet" lifestyle. Total cholesterol, LDL-cholesterol, HDL-cholesterol and Triglycerides were determined using standard cholesterol LDL precipitating reagents/kits. RESULTS: The mean age of the subjects was 41.59 +/- 8.22 years (range 29 to 58 years) with male to female ratio of 1:1.2. Mean total cholesterol was 180.69 +/- 36.248 mg/dl (4.67 +/- 0.94 mmol/L), LDL cholesterol 122.68 +/- 44.42 mg/dl (3.17 +/- 1.15 mmol/L), HDL-cholesterol 37.47 +/- 9.91 mg/dl (0.96 +/- 0.26 mmol/L) and Triglyceride 83.139 +/- 66.888 mg/dl (0.94 +/- 0.76 mmol/L). Using the Third Report of the NCEP Expert Panel on Detection. Evaluation and Treatment of high blood cholesterol in Adults (ATP III) definition and risk classification, 5% of the study population had hypercholesterolaemia, 23% elevated total serum cholesterol, 51% elevated LDL-cholesterol and 60% low HDL-cholesterol, with females recording better overall lipid profile. CONCLUSION: Dyslipidaemia was highly prevalent in the population studied, with low HDL-cholesterol being the most frequent lipid abnormality. Dyslipidaemia is becoming a serious health problem in the developing world also, even among the apparently healthy, and necessitates periodic lipid profile screening. |
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Authors:
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C U Odenigbo; O C Oguejiofor; U M Odenigbo; C C Ibeh; C N Ajaero; M A C Odike |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Nigerian journal of clinical practice Volume: 11 ISSN: 1119-3077 ISO Abbreviation: Niger J Clin Pract Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2009-03-26 Completed Date: 2009-04-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101150032 Medline TA: Niger J Clin Pract Country: Nigeria |
Other Details:
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Languages: eng Pagination: 330-5 Citation Subset: IM |
Affiliation:
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Department of Medicine, Nnamdi Azikiwe University Teaching Hospital, Nnewi Anambra State, Nigeria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cholesterol / blood* Cholesterol, HDL / blood* Cholesterol, LDL / blood* Cross-Sectional Studies Dyslipidemias / blood, diagnosis, epidemiology* Female Humans Male Middle Aged Nigeria / epidemiology Prevalence Questionnaires Risk Factors Sex Distribution Socioeconomic Factors Triglycerides / blood* |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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