| Prevalence and distribution of fasciculations in healthy adults: Effect of age, caffeine consumption and exercise. | |
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MedLine Citation:
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PMID: 19533451 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Our objective was to determine the prevalence and distribution of fasciculations in healthy adults and to assess the effect of age, caffeine and exercise. Fasciculations were studied with ultrasonography in 58 healthy adults in various age categories. Questionnaires were used to determine effect of caffeine and regular exercise on the presence of fasciculations. Finally, we tested the effect of strenuous exercise on fasciculations in 10 healthy adults. Twenty-five subjects (43%) showed fasciculations on ultrasonography, mostly in the abductor hallucis longus muscle. Fasciculations were only sporadically encountered in muscle groups above the knee. Subjects with fasciculations were significantly older than those without. Caffeine and regular physical exercise did not influence the prevalence of fasciculations. However, strenuous physical exercise caused a temporary increase in fasciculations, but only in lower leg muscles. Fasciculations above the knee should raise suspicion and may warrant further investigation. |
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Authors:
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Jiske Fermont; Ilse M P Arts; Sebastiaan Overeem; Bert U Kleine; H Jurgen Schelhaas; Machiel J Zwarts |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases Volume: 11 ISSN: 1471-180X ISO Abbreviation: Amyotroph Lateral Scler Publication Date: 2010 |
Date Detail:
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Created Date: 2010-05-04 Completed Date: 2010-08-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101283386 Medline TA: Amyotroph Lateral Scler Country: England |
Other Details:
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Languages: eng Pagination: 181-6 Citation Subset: IM |
Affiliation:
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Neuromuscular Centre Nijmegen, Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Aged Aged, 80 and over Aging* Beverages Caffeine / administration & dosage* Central Nervous System Stimulants / administration & dosage Exercise* Fasciculation / epidemiology*, ultrasonography* Female Humans Male Middle Aged Muscle, Skeletal / ultrasonography Prevalence Questionnaires Reference Values Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Central Nervous System Stimulants; 58-08-2/Caffeine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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