Document Detail

Prevalence, clinical manifestations and endoscopic features of eosinophilic esophagitis: A pathological review in China.
MedLine Citation:
PMID:  22624553     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE:   We aimed to determine the prevalence of eosinophilic esophagitis (EoE) and define its clinical and endoscopic characteristics in Chinese patients.
METHODS:   Esophageal specimens obtained from January 2006 to December 2010 in the First Affiliated Hospital of Sun Yat-sen University were reviewed, and the data on clinical characteristics and endoscopic findings of patients were obtained. Patients with eosinophils ≥15 per high power field (HPF) were identified as having EoE.
RESULTS:   A total of 12 patients met the criteria for EoE, establishing a prevalence of 0.34%. These patients presented with dysphagia (4/12, 33.3%), gastroesophageal reflux disease (GERD)-like symptoms (3/12, 25.0%), abdominal pain (3/12, 25.0%) and others (2/12, 16.7%). The most common endoscopic finding was plaques (5/12, 41.7%), and other findings were irregular Z-line (2/12, 16.7%), erosive esophagitis (2/12, 16.7%), white exudates (1/12, 8.3%), linear furrows (1/12, 8.3%), Schatzki ring (1/12, 8.3%), ulcers (1/12, 8.3%) and erythema (1/12, 8.3%).
CONCLUSIONS:   The prevalence of EoE was 0.34% in our patients. Clinicians should pay attention to patients manifested with dysphagia and GERD-like symptomes with endosopic findings of white exudates, plaques, Schatzki ring and linear furrows.
Yi Nan Shi; Shi Jun Sun; Li Shou Xiong; Qing Hua Cao; Yi Cui; Min Hu Chen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of digestive diseases     Volume:  13     ISSN:  1751-2980     ISO Abbreviation:  J Dig Dis     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101302699     Medline TA:  J Dig Dis     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  304-9     Citation Subset:  IM    
Copyright Information:
© 2012 The First Affiliated Hospital of Sun Yat-Sen University. Journal of Digestive Diseases © 2012 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd.
Department of Gastroenterology Pathology Endoscopy, First Affiliated Hospital of Sun Yat-sen University, Guangzhou Department of Pathology, Sun Yat-sen University affiliated Zhongshan Hospital, Zhongshan, Guangdong Province, China.
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