Document Detail

Prevalence and clinical features associated to bipolar disorder-migraine comorbidity: a systematic review.
MedLine Citation:
PMID:  25306379     Owner:  NLM     Status:  Publisher    
BACKGROUND: The prevalence and clinical features associated with bipolar disorders (BDs)-migraine comorbidity have been reported inconsistently across different studies, therefore warranting a systematic review on the matter.
METHODS: A systematic review was conducted in accordance with the PRISMA statement searching major electronic databases for documents indexed between January, 2000 and July, 2014. Eligible studies were those including quantitative data on prevalence rates and clinical features associated to BD-migraine comorbidity; case reports excluded. Three authors independently conducted searches, quality assessment of the studies and data extraction.
RESULTS: Several cross-sectional studies, and a handful of retrospective follow-up studies or non-systematic reviews assessed the prevalence and/or the clinical correlates of migraine-BD comorbidity. High prevalence rates and a significant burden of BD-migraine comorbidity were common findings, particularly in case of BD-II women (point-prevalence rates up to 77%), migraine with aura (up to 53%) and/or cyclothymic temperament (up to 45% of the cases).
LIMITATIONS: Some of the biases encountered in a few studies accounted by the present review may nonetheless have hampered the generalizability of the overall conclusions drawn herein.
CONCLUSIONS: BD-migraine comorbidity may comprise of a sub-phenotype of BDs requiring patient-tailored therapeutic interventions to achieve an optimal outcome. Specifically, additional studies including longitudinal follow-up studies are aimed in order to shed further light on the actual prevalence rates and clinical features associated to BD-migraine comorbidity, with a special emphasis towards the clinically suggestive potential connection between mixed features, bipolar depression, migraine, and increased risk for suicidality. PROSPERO registration number: CRD42014009335.
Michele Fornaro; Domenico De Berardis; Concetta De Pasquale; Luisa Indelicato; Rocco Pollice; Alessandro Valchera; Giampaolo Perna; Felice Iasevoli; Carmine Tomasetti; Giovanni Martinotti; Ann Sarah Koshy; Ole Bernt Fasmer; Ketil Joachim Oedegaard
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Publication Detail:
Type:  REVIEW     Date:  2014-9-28
Journal Detail:
Title:  Comprehensive psychiatry     Volume:  -     ISSN:  1532-8384     ISO Abbreviation:  Compr Psychiatry     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-10-12     Completed Date:  -     Revised Date:  2014-10-13    
Medline Journal Info:
Nlm Unique ID:  0372612     Medline TA:  Compr Psychiatry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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