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Prevalence of chronic kidney disease in hypertensive patients in ghana.
MedLine Citation:
PMID:  21529267     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Chronic kidney disease (CKD) is common in tropical Africa although there are few data on the prevalence of this disorder. Therefore we initiated a multicenter screening study to identify the prevalence and staging of CKD in 712 patients with known hypertension in four polyclinics in Accra, Ghana. We measured estimated glomerular filtration rate by the six-variable modification of diet in renal disease equation and proteinuria by the protein/creatinine ratio. All the subjects studied were Ghanaian. Of the 712 patients studied, the median age was 59 years (range 19-90 years) and 560 (78.7%) of the patients were female. The mean duration of hypertension was 4 years (range 0.1-50). The overall prevalence of CKD was 46.9% (95% CI: 43.2-50.7%); 19.1% had CKD stages 1-2 and 27.8% had CKD stages 3-5. There was no difference in age between patients with or without CKD (p = 0.12). The overall prevalence of proteinuria was 28.9% (95% CI: 25.6-32.4%); 14.7% of subjects had preexisting diabetes mellitus and their prevalence of CKD (55%; 95% CI: 42.4-62.2) did not differ from those without diabetes (46%; 95% CI: 41.9-50.0, p = 0.133). CKD is common in hypertensive patients in Ghana, with a prevalence of 46.9%. This provides justification for the inclusion of this group in CKD screening programs in Ghana.
Authors:
Charlotte Osafo; Michael Mate-Kole; Kwame Affram; Dwomoa Adu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Renal failure     Volume:  33     ISSN:  1525-6049     ISO Abbreviation:  Ren Fail     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701128     Medline TA:  Ren Fail     Country:  England    
Other Details:
Languages:  eng     Pagination:  388-92     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Ghana Medical School, University of Ghana, Accra, Ghana.
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