| Prevalence and characteristics of restless legs syndrome (RLS) in the elderly and the relation of serum ferritin levels with disease severity: Hospital-based study from Istanbul, Turkey. | |
| | |
MedLine Citation:
|
PMID: 21722973 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The RLS is an underdiagnosed condition, characterized by unpleasant sensations in the legs. Pathophysiological mechanisms may include iron deficiency as reflected by low serum ferritin levels and dopaminergic system dysfunction. The purpose of our study was to investigate the prevalence and characteristics of RLS in the elderly and the relation of serum ferritin levels with disease severity. Ambulatory 1012 (621 women, 391 men, mean age: 73.51±7.12 years) consecutive patients above 65 years who admitted to our clinic for any reason were evaluated according to the International RLS Study Group (IRLSSG) criteria: 103 patients (74 women, 29 men, mean age: 72.43±6.31) (10.18%) had RLS diagnosis. Only 9 of them had known RLS. The duration of symptoms was 4.80±4.65 years and 27 patients (26.2%) had positive family history. The average of serum ferritin levels was 39.13±23.74ng/ml and 71 patients (68.9%) had serum ferritin levels ≤50ng/ml. The disease severity was evaluated with IRLSSG rating scale. Patients were classified as severe-very severe group (n=49) and mild-moderate group (n=54). The ferritin levels of severe-very severe disease group were lower than those of mild-moderate disease group (26.01±15.82ng/ml versus 49.87±23.24ng/ml, p<0.001). Our data show that RLS is very common in the elderly and the disease is more severe in patients with lower ferritin levels. |
| | |
Authors:
|
Aslı Curgunlu; Alper Döventaş; Derya Karadeniz; Deniz Suna Erdinçler; Ayşe Kutlu Oztürk; Yesari Karter; Adnan Yaldıran; Fikret Sipahioğlu; Tanju Beğer |
Related Documents
:
|
7244743 - Manometric evaluation of esophageal disease. 9128953 - Mastication and swallowing in patients with postirradiation xerostomia. 16775593 - A simple score predicts future cardiovascular events in an inception cohort of dialysis... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-6-29 |
Journal Detail:
|
Title: Archives of gerontology and geriatrics Volume: - ISSN: 1872-6976 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-7-4 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8214379 Medline TA: Arch Gerontol Geriatr Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Internal Medicine, Istanbul University, Cerrahpasa Medical Faculty, Koca Mustafa Pasa Street, Fatih, Istanbul 34098, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Role of permanent atrial fibrillation (AF) on long-term mortality in community-dwelling elderly peop...
Next Document: The reliability and validity of the daily activities dependence on vision (DADV) scale to evaluate v...