Document Detail


Prevalence of bacterial contamination of powdered infant feeds in a hospital environment.
MedLine Citation:
PMID:  17805457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The study arose as part of a best-practice nutrition model regarding the introduction of ready-to-use (RTU) infant feeds in place of powdered infant feeds (PIFs) as a standard formula for infants under the age of 1 year who are unable to be breastfed. Internationally and locally there is grave concern regarding the safety and efficacy of mixing PIFs, especially in a hospital setting, and the resultant bacterial contamination causing enteric infections, especially in premature, immunocompromised and sick infants.
OBJECTIVE: To evaluate the prevalence of bacterial contamination of PIFs given to infants at Red Cross War Memorial Children's Hospital, Cape Town.
METHODS: Quantitative levels of bacterial contamination were determined and were expressed as colony-forming units (CFUs) per millilitre of sample. Aliquots of milk were inoculated onto agar, and the milk samples were then incubated at 25 degrees C overnight (N = 10), 30 degrees C overnight (N = 48) and 30 degrees C for 6 hours (N = 34). Post-incubation milk samples were cultured again. Contamination was defined as any positive culture before administration (i.e. pre incubation) or > 10(2) CFU/ ml after administration (i.e. post incubation).
RESULTS: Fifty samples of PIFs (N = 82) were contaminated pre incubation, with 25/82 samples (30.4%) being heavily contaminated ( >or= 10(4) CFU/ml). Post incubation, 43/92 samples (46.7%) were contaminated with > 102 CFU/ml. The acidified PIFs appeared to have some bactericidal effect against some of the organisms, but not all.
CONCLUSIONS: RTU infant feeds are sterile and are recommended for use in all hospitalised infants. The results of this study indicate that even when milk is prepared in a controlled environment there is significant bacterial contamination of PIFs post production. As RTU feeds are now readily available in South Africa every attempt should be made to use a sterile RTU system for hospitalised infants.
Authors:
L V Marino; E Goddard; A Whitelaw; L Workman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  97     ISSN:  0038-2469     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-09-06     Completed Date:  2007-10-03     Revised Date:  2014-01-09    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  534-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Colony Count, Microbial
Food Contamination / statistics & numerical data*
Food Handling
Food Microbiology*
Food Service, Hospital
Humans
Infant
Infant Formula*
Powders
Chemical
Reg. No./Substance:
0/Powders

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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