| Prevalence of asymptomatic left ventricular systolic dysfunction in hypertensive Nigerians: echocardiographic study of 832 subjects. | |
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MedLine Citation:
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PMID: 22159315 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: We sought to determine the prevalence of echocardiographically determined left ventricular systolic dysfunction in asymptomatic hypertensive subjects seen in Abeokuta, Nigeria. METHODS: Echocardiography was performed in 832 consecutive hypertensive subjects referred for cardiac evaluation over a three-year period. RESULTS: Data were obtained in 832 subjects (50.1% women) aged 56.0 ± 12.7 years (men 56.9 ± 13.3 years, women 55.0 ± 12.0 years, range 15-88). The prevalence of left ventricular systolic dysfunction (LVSD) was 18.1% in the study population (mild LVSD = 9.6%, moderate LVSD = 3.7% and severe LVSD = 4.8%). In a multivariate analysis, male gender, body mass index and LV mass were the predictors of LVSD. CONCLUSION: Significant numbers of hypertensive subjects in this study had varying degrees of left ventricular systolic dysfunction. Early introduction of disease-modifying drugs in these patients, such as angiotensin converting enzyme inhibitors or angiotensin receptor blockers may retard or prevent the progression to overt heart failure. |
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Authors:
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O S Ogah; R O Akinyemi; G D Adegbite; O I Udofia; S B Udoh; J O Adesina; O S Ojo; A A Alabi; T Majekodunmi; J K Osinfade; R F Ogundipe; A O Falase |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiovascular journal of Africa Volume: 22 ISSN: 1995-1892 ISO Abbreviation: Cardiovasc J Afr Publication Date: 2011 Nov-Dec |
Date Detail:
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Created Date: 2011-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101313864 Medline TA: Cardiovasc J Afr Country: South Africa |
Other Details:
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Languages: eng Pagination: 297-302 Citation Subset: IM |
Affiliation:
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Department of Medicine, Federal Medical Centre, Idi-Aba, Abeokuta, Ogun State, Nigeria. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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