| Prevalence of antibody to human coronaviruses 229E, OC43 and neonatal calf diarrhea coronavirus (NCDCV) in patients of Northern Italy. | |
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MedLine Citation:
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PMID: 3021524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A seroepidemiological study for detection of antibody to human coronaviruses OC43, 229E, and neonatal calf diarrhea coronavirus (NCDCV), has been carried out using sera collected from hospitalized patients or healthy persons through routine laboratory tests in Northern Italy. Patients tested were children and adults with different pathological diseases. Antibody detection was performed by using an indirect immunoperoxidase staining technique (for all viruses) and, in the case of OC43 and NCDCV, antibody detection was obtained even with a hemagglutination inhibition test and a plaque reduction neutralization assay. Results obtained show a significant difference in the prevalence of antibody to 229E between children and adult group. Furthermore, a different titer was observed, within the two groups, between patients affected by hematological diseases (leukemia) and patients with other diseases. Finally, our data seem to confirm previous studies reporting a very high prevalence of antibody to coronavirus OC43 but a less detectable seropositivity to coronavirus 229E. |
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Authors:
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P M Cereda; L Pagani; E Romero |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of epidemiology Volume: 2 ISSN: 0393-2990 ISO Abbreviation: Eur. J. Epidemiol. Publication Date: 1986 Jun |
Date Detail:
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Created Date: 1986-12-16 Completed Date: 1986-12-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8508062 Medline TA: Eur J Epidemiol Country: ITALY |
Other Details:
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Languages: eng Pagination: 112-7 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies, Viral / analysis* Coronaviridae / immunology* Coronaviridae Infections / epidemiology*, immunology Humans Italy |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral |
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