Document Detail


Prevalence of antibodies to hepatitis C virus, HIV and human T-cell leukaemia/lymphoma viruses in injecting drug users in Tayside, Scotland, 1993-7.
MedLine Citation:
PMID:  11293687     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prevalence of blood-borne viruses in injecting drug users (IDUs) in Tayside, Scotland was determined by testing serum samples from IDUs who underwent attributable HIV antibody testing during 1993-7. The prevalence of antibodies to HIV was 29/802, (3.6%); to hepatitis C virus (HCV) 451/691, (65.3%); and to human T-cell leukaemia/lymphoma viruses type 1 and 2 (HTLV) 0/679, (0.0%). The prevalence of HIV and HCV antibodies were higher in subjects over the age of 25 (P = 0.03 and P = 0.001, respectively). During 1993-7 the prevalence of HCV fell only in younger female IDUs (P < 0.01). HIV prevalence has declined dramatically since 1985, when a rate of 40% was recorded in similar populations. Harm reduction measures have failed to control HCV the spread of infection among IDUs in Tayside, as indicated by the high proportion of antibody positive IDUs, particularly males under the age of 25. Future studies should address the nature and effective reduction of continuing risk taking among IDUs in Tayside.
Authors:
P G McIntyre; D A Hill; K Appleyard; A Taylor; S Hutchinson; D J Goldberg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Epidemiology and infection     Volume:  126     ISSN:  0950-2688     ISO Abbreviation:  Epidemiol. Infect.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-04-09     Completed Date:  2001-04-26     Revised Date:  2010-05-17    
Medline Journal Info:
Nlm Unique ID:  8703737     Medline TA:  Epidemiol Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  97-101     Citation Subset:  IM    
Affiliation:
Department of Medical Microbiology, Ninewells Hospital & Medical School, Dundee, UK.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Antibodies, Viral / analysis*,  immunology
Deltaretrovirus Antibodies / analysis,  immunology
Deltaretrovirus Infections / epidemiology*,  immunology,  prevention & control
Female
HIV Antibodies / analysis,  immunology
HIV Infections / epidemiology*,  immunology,  prevention & control
Hepatitis C / epidemiology*,  immunology,  prevention & control
Hepatitis C Antibodies / analysis,  immunology
Humans
Male
Prevalence
Risk Factors
Scotland / epidemiology
Substance Abuse, Intravenous / blood*,  complications
Chemical
Reg. No./Substance:
0/Antibodies, Viral; 0/Deltaretrovirus Antibodies; 0/HIV Antibodies; 0/Hepatitis C Antibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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