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Prevalence of anemia and risk of adverse bleeding effect of drugs: implication for therapy.
MedLine Citation:
PMID:  22506109     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This study aimed to evaluate the progress in reduction of prevalence of anemia in rural Australia. It also investigates the prevalence of hypoviscosity in anaemia with a view to determine the fraction of anaemic patients at risk of drug-inducible exacerbation of anemia. Archived clinical pathology data (N = 130, 354) for the period of 1999 to 2008 were utilized. The prevalence of anemia and hypoviscosity was evaluated by working out (i) the number that fell within anemia definition as a percentage of the population and (ii) the number that fell within hypoviscosity definition as a percentage of anemic patients. The prevalence in anemic diabetes and dyslipidaemia was further determined. There was progressive reduction in anemia from 6.1% to 3.2% over the ten years period. Prevalence of anemia is statistically significantly higher in males than in females (P < 0.0001), but protein level is lower in anemic females than in anemic males (P < 0.01). The results further show that up to 75% of anemic patients may benefit from NSAID or salicylates. This paper highlights differences between genders. It suggests more concerted effort in men's health and speculates a new factor to investigate in women's health.
Authors:
Ezekiel Uba Nwose
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Publication Detail:
Type:  Journal Article     Date:  2012-02-28
Journal Detail:
Title:  Anemia     Volume:  2012     ISSN:  2090-1275     ISO Abbreviation:  Anemia     Publication Date:  2012  
Date Detail:
Created Date:  2012-04-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101536021     Medline TA:  Anemia     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  795439     Citation Subset:  -    
Affiliation:
Institute of Clinical Pathology & Medical Research, Nepean Hospital Pathology, Kingswood NSW 2747, Australia.
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