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Prevalence of adiposity and associated cardiometabolic risk factors in the samoan genome-wide association study.
MedLine Citation:
PMID:  24799123     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To describe the prevalence of obesity-related noncommunicable diseases (NCDs) and associated risk factors in a sample of Samoan adults studied in 2010 as part of a genome-wide assocation study (GWAS) for obesity related traits.
METHODS: Anthropometric and biochemical data collected from n = 3,475 participants (n = 1,437 male; n = 2,038 female) aged 24.5 to <65 years were used to describe the prevalence of obesity, diabetes, hypertension, and dyslipidemia within the study sample. One way analysis of variance, χ(2) tests, and binary logistic regression were used to identify differences in disease and risk factor prevalence by 10-year age group, gender, or by census region of residence.
RESULTS: Obesity was highly prevalent among the study sample; 64.6% of females and 41.2% of males were obese according to Polynesian cutoffs (BMI ≥ 32 kg/m(2) ). Females were less likely than males to have hypertension (31.7% vs. 36.7%) but equally likely to have diabetes (17.8% vs. 16.4%). With the exception of obesity and low HDL-cholesterol in females only, there were significant differences in the prevalence of all NCDs and associated risk factors by age group, with the oldest age group (55 to <65 years) most affected. In both sexes, residents of the Apia Urban Area were at significantly greater risk of obesity, diabetes, low HDL-cholesterol, and high triglycerides than residents of the more rural Savaii region.
CONCLUSIONS: The phenotypic characteristics of this sample provide evidence of a continuation of previously reported temporal trends toward obesity and its associated disorders. Attention must be paid to the critical NCD situation in Samoa. Am. J. Hum. Biol., 2014. © 2014 Wiley Periodicals, Inc.
Nicola L Hawley; Ryan L Minster; Daniel E Weeks; Satupaitea Viali; Muagututia Sefuiva Reupena; Guangyun Sun; Hong Cheng; Ranjan Deka; Stephen T McGarvey
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-5
Journal Detail:
Title:  American journal of human biology : the official journal of the Human Biology Council     Volume:  -     ISSN:  1520-6300     ISO Abbreviation:  Am. J. Hum. Biol.     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8915029     Medline TA:  Am J Hum Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Wiley Periodicals, Inc.
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