Document Detail

Prevalence of actinic skin lesions in patients with basal cell carcinoma of the head: a case-control study.
MedLine Citation:
PMID:  22569613     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the prevalence of actinic skin lesions in patients with basal cell carcinoma of the head.
METHODS: A case-control study was carried out. Cases were patients with primary, solid basal cell carcinoma of the head, less than two centimeters in diameter; and as controls, patients with other dermatoses. Constitutional and behavioral variables were analyzed, as well as actinic lesions.
RESULTS: One hundred twenty cases and 360 controls were evaluated. Facial milia (OR = 2.3), leukoderma punctata of the upper limbs (OR = 2.9), and cutis rhomboidalis nuchae (OR = 1.8) were associated with neoplasms regardless of other variables, suggesting a risk phenotype. There was also association with light hair and eye color phenotypes, family genetics, and cumulative sun exposure. Sunburn, smoking, and alcoholism were not identified as risk factors. The use of sunscreens showed no evidence of protection; however, the control group consisted of dermatology patients who are often prescribed sunscreens.
CONCLUSION: Actinic lesions were more prevalent in patients with solid basal cell carcinoma of the head than in controls, especially milia, cutis rhomboidalis nuchae, and leukoderma punctata, regardless of other known risk factors.
Valquíria Pessoa Chinem; Hélio Amante Miot
Related Documents :
21204043 - Mesenteric angiography of patients with gastrointestinal tract hemorrhages: a single ce...
21172843 - Tdp-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia.
2801193 - Macrocytosis as an indicator of human disease.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista da Associação Médica Brasileira (1992)     Volume:  58     ISSN:  0104-4230     ISO Abbreviation:  Rev Assoc Med Bras     Publication Date:    2012 Mar-Apr
Date Detail:
Created Date:  2012-05-09     Completed Date:  2013-01-16     Revised Date:  2013-06-10    
Medline Journal Info:
Nlm Unique ID:  9308586     Medline TA:  Rev Assoc Med Bras     Country:  Brazil    
Other Details:
Languages:  eng; por     Pagination:  188-96     Citation Subset:  IM    
Departament of Dermatology and Radiotherapy, Universidade Estadual Paulista (FMB-UNESP), Botucatu, SP, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Brazil / epidemiology
Carcinoma, Basal Cell / complications,  epidemiology*,  genetics
Case-Control Studies
Genetic Predisposition to Disease
Head and Neck Neoplasms / complications,  epidemiology*,  genetics
Keratosis, Actinic / epidemiology*,  etiology
Risk Factors
Skin Neoplasms / complications,  epidemiology*,  genetics
Skin Pigmentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Immunohistochemical profile and clinical-pathological variables in breast cancer.
Next Document:  Differences in body fat distribution assessed by ultrasonography in patients receiving antiretrovira...