Document Detail


Prevalence of actinic skin lesions in patients with basal cell carcinoma of the head: a case-control study.
MedLine Citation:
PMID:  22569613     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the prevalence of actinic skin lesions in patients with basal cell carcinoma of the head.
METHODS: A case-control study was carried out. Cases were patients with primary, solid basal cell carcinoma of the head, less than two centimeters in diameter; and as controls, patients with other dermatoses. Constitutional and behavioral variables were analyzed, as well as actinic lesions.
RESULTS: One hundred twenty cases and 360 controls were evaluated. Facial milia (OR = 2.3), leukoderma punctata of the upper limbs (OR = 2.9), and cutis rhomboidalis nuchae (OR = 1.8) were associated with neoplasms regardless of other variables, suggesting a risk phenotype. There was also association with light hair and eye color phenotypes, family genetics, and cumulative sun exposure. Sunburn, smoking, and alcoholism were not identified as risk factors. The use of sunscreens showed no evidence of protection; however, the control group consisted of dermatology patients who are often prescribed sunscreens.
CONCLUSION: Actinic lesions were more prevalent in patients with solid basal cell carcinoma of the head than in controls, especially milia, cutis rhomboidalis nuchae, and leukoderma punctata, regardless of other known risk factors.
Authors:
Valquíria Pessoa Chinem; Hélio Amante Miot
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Revista da Associação Médica Brasileira (1992)     Volume:  58     ISSN:  0104-4230     ISO Abbreviation:  Rev Assoc Med Bras     Publication Date:    2012 Mar-Apr
Date Detail:
Created Date:  2012-05-09     Completed Date:  2013-01-16     Revised Date:  2013-06-10    
Medline Journal Info:
Nlm Unique ID:  9308586     Medline TA:  Rev Assoc Med Bras     Country:  Brazil    
Other Details:
Languages:  eng; por     Pagination:  188-96     Citation Subset:  IM    
Affiliation:
Departament of Dermatology and Radiotherapy, Universidade Estadual Paulista (FMB-UNESP), Botucatu, SP, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brazil / epidemiology
Carcinoma, Basal Cell / complications,  epidemiology*,  genetics
Case-Control Studies
Female
Genetic Predisposition to Disease
Head and Neck Neoplasms / complications,  epidemiology*,  genetics
Humans
Keratosis, Actinic / epidemiology*,  etiology
Male
Prevalence
Risk Factors
Skin Neoplasms / complications,  epidemiology*,  genetics
Skin Pigmentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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