Document Detail


Prevalence of the ST239 clone of methicillin-resistant Staphylococcus aureus and differences in antimicrobial susceptibilities of ST239 and ST5 clones identified in a Korean hospital.
MedLine Citation:
PMID:  16081886     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A total of 188 nonduplicate methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained between 2001 and 2004 in a university hospital in Daegu, Korea, were analyzed for their clonal types by molecular typing techniques, including multilocus sequence typing, spaA typing, staphylococcal chromosomal cassette mec (SCCmec) typing, and pulsed-field gel electrophoresis (PFGE). They were examined for their antimicrobial susceptibilities. The majority (87%) of MRSA isolates belonged to sequence type 239 (ST239; n = 100; 53%) and ST5 (n = 63, 34%) on the basis of sequence typing. MRSA isolates belonging to ST239 were genotypically homogeneous, while those belonging to ST5 showed variations in spaA type, SCCmec type, and PFGE patterns. The rates of resistance of the MRSA isolates belonging to ST239 to trimethoprim, sulfamethoxazole, tobramycin, gentamicin, erythromycin, and tetracycline were significantly higher than those of the isolates belonging to ST5 (P < 0.05). This study demonstrated that the ST239 clone, while rarely detected in Korea, was prevalent and that the antimicrobial susceptibility of the ST239 clone was significantly different from that of the ST5 clone.
Authors:
Hwa Yun Cha; Dong Chan Moon; Chul Hee Choi; Jae Young Oh; Young Sook Jeong; Yoo Chul Lee; Sung Yong Seol; Dong Taek Cho; Hyun-Ha Chang; Shin-Woo Kim; Je Chul Lee
Related Documents :
20339016 - Epidemic meticillin-resistant staphylococcus aureus (emrsa-15) variants detected in hea...
12205056 - Multilocus sequence typing (mlst) shows that the 'iberian' clone of methicillin-resista...
15181496 - Community-acquired methicillin-resistant staphylococcus aureus liver abscess in a patie...
19396516 - A rapid screening method for panton-valentine leucocidin-positive community-acquired me...
20083146 - Calorimetric control for high cell density cultivation of a recombinant escherichia col...
6725296 - A method for in vivo quantitative occlusal strain and stress analysis.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  43     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-05     Completed Date:  2005-09-15     Revised Date:  2010-09-21    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3610-4     Citation Subset:  IM    
Affiliation:
Department of Microbiology, Kyungpook National University School of Medicine, 101, Dongin-dong, Jung-gu, Daegu 700-422, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Methicillin Resistance*
Microbial Sensitivity Tests
Staphylococcus aureus / classification,  drug effects*,  genetics
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Improvement of Lyme borreliosis serodiagnosis by a newly developed recombinant immunoglobulin G (IgG...
Next Document:  Comparison of five repetitive-sequence-based PCR typing methods for molecular discrimination of Salm...