Document Detail


Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland.
MedLine Citation:
PMID:  22457699     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Routes of transmission of hepatitis B virus (HBV)/HIV infections are similar and there is a significant rate of co-infection in patients. A study was recently carried out in NHS Fife, Scotland from February 2007 - February 2008 to estimate the prevalence of HBV/HIV co-infection, occult HBV infection and immunisation status against HBV in a cohort of patients with HIV attending the departments of infectious diseases and genitourinary medicine.
METHODS: Case notes were reviewed retrospectively (n = 70). Details on patient demographics, risk category, nadir/current CD4 count, HIV viral load and vaccination history were analysed. HBV markers (HBsAg/anti-HBs/anti-HBc/HBV DNA) and alanine transaminase (ALT) levels were tested prospectively if these tests had not been carried out in the previous 12 months.
RESULTS AND CONCLUSION: Prevalence of HBV/HIV co-infection was 5.6% of which 2.8% of patients had occult infection and 22.9% had evidence of previous exposure. Although HBV is preventable by vaccination, only 24.2% of patients had been vaccinated against it. Improvements could therefore be made in the field of prevention with vaccination and monitoring the immune response in this cohort.
KEYWORDS: Prevalence; Immunization status; Hepatitis B Virus; HIV.
Authors:
Lukman Hakeem; Grace Thomson; Eleanor McCleary; Diptendu Bhattacharyya; Indranil Banerjee
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Publication Detail:
Type:  Journal Article     Date:  2010-02-08
Journal Detail:
Title:  Journal of clinical medicine research     Volume:  2     ISSN:  1918-3003     ISO Abbreviation:  J Clin Med Res     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2012-03-29     Completed Date:  2012-08-23     Revised Date:  2012-09-10    
Medline Journal Info:
Nlm Unique ID:  101538301     Medline TA:  J Clin Med Res     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  34-8     Citation Subset:  -    
Affiliation:
Infectious Diseases Unit, Victoria Hospital (NHS Fife), Kirkcaldy, Fife, Scotland, UK.
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