Document Detail


Prevalence of hyperkalemia among hemodialysis patients in Egypt.
MedLine Citation:
PMID:  20030523     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Hyperkalemia is a frequent problem in patients with end stage renal disease (ESRD) on maintenance hemodialysis and is often attributed as a cause of deaths in these patients. The aim of this study was to estimate the prevalence of hyperkalemia among Egyptian hemodialysis patients. PATIENTS AND METHODS: 400 ESRD patients on maintenance hemodialysis were enrolled in the study. They were allowed their usual diets and medications during the study periods. For all patients, history and clinical examinations and serum potassium level was measured three times--pre- and post-1st session and pre-next session--at two successive sessions of hemodialysis. RESULTS: The results of this study showed that the prevalence of hyperkalemia was 41.2%, 6.5%, and 66.9% of pre- and post-dialysis and before the next session of dialysis, respectively. Hyperkalemia significantly correlates with potassium-rich diets, non-compliant patients, two sessions of hemodialysis per week, and constipation in ESRD patients during the study periods. Serum potassium level was significantly higher in anuric ESRD patients than those who had residual renal function, patients using acetate dialysate than those using bicarbonate dialysate, and patients with low blood flow rate than those with higher blood flow rates. There was a non-significant correlation between serum potassium and ACEls, B-blockers, or diabetes. CONCLUSION: Hyperkalemia is a frequent problem in patients with end stage renal disease in Egypt. Hyperkalemia significantly correlates with a potassium-rich diet and inadequate dialysis either by prescription or non-compliance. Thrice weekly bicarbonate dialysis with higher blood pump flow rate had better elimination of potassium.
Authors:
Essam Khedr; Saeed Abdelwhab; Magdy El-Sharkawy; Magdy El-Sharkay; Medhat Ali; Kadrey El Said
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Renal failure     Volume:  31     ISSN:  1525-6049     ISO Abbreviation:  Ren Fail     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-24     Completed Date:  2010-03-30     Revised Date:  2010-05-26    
Medline Journal Info:
Nlm Unique ID:  8701128     Medline TA:  Ren Fail     Country:  England    
Other Details:
Languages:  eng     Pagination:  891-8     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine and Nephrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angiotensin-Converting Enzyme Inhibitors / adverse effects
Constipation / complications
Diabetes Complications / epidemiology
Dialysis Solutions / adverse effects
Diet / adverse effects
Egypt / epidemiology
Female
Humans
Hyperkalemia / epidemiology*,  etiology
Kidney Failure, Chronic / complications,  epidemiology*,  metabolism
Male
Middle Aged
Potassium / blood
Prevalence
Urine
Young Adult
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Dialysis Solutions; 7440-09-7/Potassium
Comments/Corrections
Erratum In:
Ren Fail. 2010 Jan;32(1):151
Note: El-Sharkay, Magdy [corrected to El-Sharkawy, Magdy]

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