| Prevalence and genotypic characteristics of Clostridium difficile in a closed and integrated human and swine population. | |
| | |
MedLine Citation:
|
PMID: 21724899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Recently, an apparent rise in the number of cases attributed to community-acquired Clostridium difficile infection has led researchers to explore additional sources of infection. The finding of C. difficile in food animals and retail meat has raised concern about potential food-borne and occupational exposures. The objective of this study was to compare C. difficile isolated from a closed population of healthy individuals consisting of both humans and swine in order to investigate possible food safety and occupational risks for exposure. Using a multistep enrichment isolation technique, we identified 11.8% of the human wastewater samples and 8.6% of the swine samples that were positive for C. difficile. The prevalences of C. difficile in swine production groups differed significantly (P < 0.05); however, the prevalences in the two human occupational group cohorts did not differ significantly (P = 0.81). The majority of the human and swine isolates were similar based on multiple typing methods. The similarity in C. difficile prevalence in the human group cohorts suggests a low occupational hazard, while a greatly decreased prevalence of C. difficile in later-stage swine production groups suggests a diminished risk for food-borne exposure. The similarity of strains in the two host species suggests the possibility of a common environmental source for healthy individuals in a community setting. |
| | |
Authors:
|
Keri N Norman; H Morgan Scott; Roger B Harvey; Bo Norby; Michael E Hume; Kathleen Andrews |
Related Documents
:
|
23010829 - Cutaneous hypersensitivity to gluten. 20627519 - Cardiac arrest due to food asphyxiation in adults: resuscitation profiles and outcomes. 22062719 - Pathogens on meat and infection in animals - establishing a relationship using campylob... 23241129 - Magnesium stearate: an underestimated allergen. 23739339 - Vital signs: listeria illnesses, deaths, and outbreaks - united states, 2009-2011. 23549639 - Risk factors for body composition abnormalities in systemic sclerosis. 106089 - The relationship between energy-dependent phagocytosis and the rate of oxygen consumpti... 8454959 - Acquisition of a spatially defined operant with delayed reinforcement. 10181519 - Medical devices; neurological devices; classification of cranial orthosis--fda. final r... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S. Date: 2011-07-01 |
Journal Detail:
|
Title: Applied and environmental microbiology Volume: 77 ISSN: 1098-5336 ISO Abbreviation: Appl. Environ. Microbiol. Publication Date: 2011 Aug |
Date Detail:
|
Created Date: 2011-08-05 Completed Date: 2011-12-15 Revised Date: 2013-05-24 |
Medline Journal Info:
|
Nlm Unique ID: 7605801 Medline TA: Appl Environ Microbiol Country: United States |
Other Details:
|
Languages: eng Pagination: 5755-60 Citation Subset: IM |
Affiliation:
|
Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas 77843, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bacterial Typing Techniques Clostridium difficile / classification, genetics*, isolation & purification* Cohort Studies Electrophoresis, Gel, Pulsed-Field Feces / microbiology* Food Safety Genotype Humans Logistic Models Prevalence Risk Factors Seasons Swine / microbiology* Water Microbiology |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Characterization of methicillin-resistant Staphylococcus aureus isolates from food and food products...
Next Document: Associations of physical activity and television viewing time with retinal vascular caliber in a mul...