Document Detail


Prevalence of Escherichia coli O157:H7 among diarrhoeic HIV/AIDS patients in the Eastern Cape Province-South Africa.
MedLine Citation:
PMID:  18819543     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigated the prevalence of Escherichia coli O157:H7 in the stool of confirmed and non-confirmed diarrhoeic HIV/AIDS patients. Escherichia coli O157:H7 was isolated by culture-based and immunomagnetic separation from three hundred and sixty stool swabs. Identification was by conventional IMViC, 20E API and molecular techniques. Confirmed and non-confirmed diarrhoeic HIV/AIDS patients had 56.5% (74/131) and 43.5% (57/131) respectively of E. coli O157:H7. Molecular results indicated that the prevalence of E. coli O157:H7 was 12.16% (9/74) and 8.77% (5/57) from stool swabs of confirmed and non-confirmed diarrhoeic HIV/AIDS patients. Antimicrobial resistance was higher for E. coli O157:H7 isolates from stools of confirmed HIV/AIDS than it was for non-confirmed HIV/AIDS patients. Escherichia coli O157:H7 might be a silent cause of diarrhoea in HIV/AIDS patients. It is recommended that HIV/AIDS patients with diarrhoea should be screened for E. coli O157:H7 and surveillance programmes for these bacteria should be established in both urban and rural areas of South Africa.
Authors:
B O Abong'o; M N B Momba; V K Malakate; J N Mwambakana
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pakistan journal of biological sciences: PJBS     Volume:  11     ISSN:  1028-8880     ISO Abbreviation:  Pak. J. Biol. Sci.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-09-29     Completed Date:  2008-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101247723     Medline TA:  Pak J Biol Sci     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  1066-75     Citation Subset:  IM    
Affiliation:
Department of Biochemistry and Microbiology, School of Science and Technology, University of Fort Hare, P/Bag X1314, Alice 5700, South Africa.
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MeSH Terms
Descriptor/Qualifier:
Acquired Immunodeficiency Syndrome / complications,  epidemiology*,  ethnology,  microbiology*
Adolescent
Adult
Age Distribution
Aged
Anti-Bacterial Agents / pharmacology
Child
Diarrhea / complications,  epidemiology*,  microbiology*
Escherichia coli O157 / drug effects,  genetics,  isolation & purification*
Feces / microbiology
Genes, Bacterial
Humans
Middle Aged
Prevalence
South Africa / epidemiology
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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