Document Detail

Prevalence and diagnosis of primary aldosteronism.
MedLine Citation:
PMID:  20665130     Owner:  NLM     Status:  In-Process    
Primary aldosteronism (PA) is a common cause of arterial hypertension: in the PA Prevalence in Hypertensives (PAPY) Study, the prevalence of PA was 11.2% in consecutive referred hypertensive patients. When adrenal vein sampling (AVS) is available, two thirds of the cases can be attributed to a tumor and one third of cases are idiopathic; the opposite is seen when AVS is unavailable. Thus, AVS influences the relative prevalence rate of the main subtypes of PA. When adrenalectomy is undertaken based on AVS, almost 100% of patients are cured of hyperaldosteronism, one third are cured of hypertension, and 52% are markedly improved in terms of blood pressure control. Persistent hypertension can be predicted by a long history of hypertension and by the presence of excessive cardiovascular damage, including vascular remodeling. Therefore, an early diagnosis is crucial to achieve cure. This review discusses the implications of the high prevalence of PA for its diagnostic strategy.
Gian Paolo Rossi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current hypertension reports     Volume:  12     ISSN:  1534-3111     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  342-8     Citation Subset:  IM    
DMCS-Clinica Medica 4, Policlinico Universitario, Via Giustiniani 2, 35126, Padova, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The influence of electric fields on hippocampal neural progenitor cells.
Next Document:  Virus infections: lessons from pancreas histology.