Document Detail


Prevalence of Congenital Heart Disease Assessed by Echocardiography in 2067 Consecutive Newborns.
MedLine Citation:
PMID:  21362039     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aim:  There are discrepancies in the reported prevalence of congenital heart disease (CHD). This study prospectively evaluated the prevalence of CHD in consecutive newborns using echocardiographic screening. Methods:  A cohort screening study was conducted in an unselected series of all live-birth newborns. Two-dimensional and color Doppler echocardiography was performed at 0 to 4 days of life in 2067 consecutive neonates who were born at the Hamamatsu University Hospital, Japan, between May 2005 and April 2010. Results:  There were 104 cases of CHD in the 2067 live births. Ventricular septal defect and patent ductus arteriosus were the most frequent cardiac abnormalities. The prevalence of newborns with CHD who had signs or symptoms of CHD and/or required invasive intervention was 21.3 per 1000 live births. However, 60 patients (29.0 per 1000 live births) with CHD were asymptomatic and did not need invasive intervention. The overall prevalence of CHD in this series was 50.3 per 1000 live births. Conclusion:  This prospective study using echocardiography for all newborns shows a higher prevalence of CHD than almost all of the previous studies.
Authors:
Takamichi Ishikawa; Satoru Iwashima; Akira Ohishi; Yuichi Nakagawa; Takehiko Ohzeki
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-1
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Acta Paediatrica © 2011 Foundation Acta Paediatrica.
Affiliation:
Department of Pediatrics, Hamamatsu University School of Medicine, Japan.
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