Document Detail


Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae and repeat infection among pregnant urban adolescents.
MedLine Citation:
PMID:  20938375     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Negative maternal and fetal consequences associated with Chlamydia trachomatis and Neisseria gonorrhoeae during pregnancy make diagnosis essential. The Centers for Disease Control and Prevention recommend routine screening for sexually transmitted infections at the first prenatal visit, and third trimester repeat screening, specifically for C. trachomatis, is recommended for women under age 25 or at increased infection risk. The effect of repeat screening on diagnosis during pregnancy is not well documented among adolescents.
METHODS: A prospective cohort of 125 pregnant adolescents with at least one prenatal screening for C. trachomatis and N. gonorrhoeae was analyzed. All participants received prenatal care and delivered at one urban teaching hospital in Washington, DC. Screening results were documented for both sexually transmitted infections. Descriptive and univariate analyses were performed to describe disease prevalence.
RESULTS: Of pregnant adolescents, 31% were diagnosed with either C. trachomatis or N. gonorrhoeae infection during pregnancy. Of the 75% (95/125) of patients who had more than one screening test, 11% (10/95) had a reinfection, and 7% (7/95) had a new infection on repeat testing. Nine percent (9/95) had recurrent C. trachomatis, whereas 4% (4/95) had a new diagnosis. Three percent (3/95) had recurrent N. gonorrhoeae, whereas 4% (4/95) had a new diagnosis. Some experienced coinfection at either initial or repeat testing.
CONCLUSIONS: Screening for C. trachomatis and N. gonorrhoeae is recommended during pregnancy. In this sample of pregnant adolescents, the overall high incidence and recurrence of C. trachomatis and N. gonorrhoeae support Centers for Disease Control and Prevention screening and rescreening recommendations, regardless of initial test results.
Authors:
Erica K Berggren; Loral Patchen
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Sexually transmitted diseases     Volume:  38     ISSN:  1537-4521     ISO Abbreviation:  Sex Transm Dis     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-11     Completed Date:  2011-06-22     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  7705941     Medline TA:  Sex Transm Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  172-4     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC 27599, USA. erica_berggren@med.unc.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Chlamydia Infections / diagnosis,  epidemiology*,  microbiology
Chlamydia trachomatis* / isolation & purification
District of Columbia
Female
Gonorrhea / diagnosis,  epidemiology*,  microbiology
Humans
Mass Screening*
Neisseria gonorrhoeae* / isolation & purification
Practice Guidelines as Topic
Pregnancy
Pregnancy Complications, Infectious / diagnosis,  epidemiology*,  microbiology
Pregnancy Trimester, First
Pregnancy Trimester, Third
Prenatal Care / standards
Prevalence
Prospective Studies
Recurrence
Urban Population / statistics & numerical data
Grant Support
ID/Acronym/Agency:
1 T32 HD-30672-01/HD/NICHD NIH HHS; APHPA002026-04-00//PHS HHS; T32 HD040672/HD/NICHD NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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