| Prevalence of CagA and VacA antibodies in children with Helicobacter pylori-associated peptic ulcer compared to prevalence in pediatric patients with active or nonactive chronic gastritis. | |
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MedLine Citation:
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PMID: 10973467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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VacA and CagA serological responses were detected in pediatric patients: 44 and 56%, respectively, in peptic ulcer (PU) patients, 33.3 and 44.4% in active chronic gastritis (ACG) patients, and 23.2 and 39.2% in non-ACG patients. Higher seroprevalence to CagA+VacA and to CagA+VacA+35-kDa antigen was found among PU patients. However, a low level of sensitivity and specificity was found for indirect detection of PU patients. |
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Authors:
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T Alarcón; M J Martínez; P Urruzuno; M L Cilleruelo; D Madruga; M Sebastian; D Domingo; J C Sanz; M López-Brea |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical and diagnostic laboratory immunology Volume: 7 ISSN: 1071-412X ISO Abbreviation: Clin. Diagn. Lab. Immunol. Publication Date: 2000 Sep |
Date Detail:
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Created Date: 2000-10-20 Completed Date: 2000-10-20 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 9421292 Medline TA: Clin Diagn Lab Immunol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 842-4 Citation Subset: IM |
Affiliation:
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Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain. talarcon@helicobacterspain.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antibodies, Bacterial / blood* Antigens, Bacterial / immunology* Bacterial Proteins / immunology* Blotting, Western / methods Child Child, Preschool Chronic Disease Female Gastritis / blood, epidemiology, immunology* Helicobacter Infections / blood, epidemiology, immunology* Helicobacter pylori / immunology Humans Male Peptic Ulcer / blood, epidemiology, immunology* Predictive Value of Tests Sensitivity and Specificity Seroepidemiologic Studies Spain / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial; 0/Antigens, Bacterial; 0/Bacterial Proteins; 0/VacA protein, Helicobacter pylori; 0/cagA protein, Helicobacter pylori |
| Comments/Corrections | |
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