Document Detail

Prevalance of Chlamydia trochomatis, Ureaplasma urealyticum and Mycoplasma hominis infections in the unexplained infertile women.
MedLine Citation:
PMID:  17160569     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To prospectively investigate the prevalence of Chlamydia trachomatis (CT), Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU) in the cervical canal and pouch of Douglas in unexplained infertile women and compare it to healthy controls in the Turkish population. MATERIALS AND METHODS: A total of 31 women presenting with a history of infertility [n = 24 (77%) primary infertility, n = 7 (23%) secondary infertility] between 20 and 38 years of age and 31 women willing to have tubal ligation between 30 and 41 years of age were consecutively included into this study. Specimens were taken from intra-abdominal washings and from the cervical canal. CT, MH and UU were detected with polymerase chain reaction (PCR). RESULTS: Results of 62 women were analyzed. None of the participants met the criteria for salpingitis during laparoscopy. The most common infection in the cervical canal in both groups was UU, which was detected in 13 cases of infertile patients and 11 controls (P = 0.602). Cervical chlamydial and mycoplasmic infection was detected in one case each in infertile and control patients. Neither MH nor UU were obtained from the pouch of Douglas in both groups. Only CT was present in peritoneal fluid of an infertile woman who had also a concomitant chlamydial infection in the cervical canal. CONCLUSION: Demonstration of cervical colonization of CT by PCR may be a promising method for the detection of asymptomatic pelvic infection in patients with unexplained infertility. However, screening for MH and UU is not cost-effective due to similar low rates of detection.
Melih A Guven; Umut Dilek; Ozlem Pata; Saffet Dilek; Pinar Ciragil
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study     Date:  2006-12-10
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  276     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-07-26     Completed Date:  2008-03-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  219-23     Citation Subset:  IM    
Faculty of Medicine, Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
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MeSH Terms
Case-Control Studies
Cervix Uteri / microbiology
Chlamydia Infections / complications,  epidemiology*
Chlamydia trachomatis*
Cross-Sectional Studies
Douglas' Pouch / microbiology
Infertility, Female / epidemiology*,  etiology,  microbiology*
Mycoplasma Infections / complications,  epidemiology*
Mycoplasma hominis*
Prospective Studies
Ureaplasma Infections / complications,  epidemiology*
Ureaplasma urealyticum*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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