| Pretreatment with dexmedetomidine: altered indices of anesthetic depth for halothane in the neuraxis of cats. | |
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MedLine Citation:
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PMID: 10072018 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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IMPLICATIONS: The anesthetic adjuvant dexmedetomidine seems to differentially alter central nervous system-mediated indices of anesthetic action. Lower brainstem or spinal determinants of anesthetic depth (movement and hemodynamic responses) are more attenuated than those of higher brain functions, such as the electroencephalogram. |
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Authors:
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W T Schmeling; P Ganjoo; M Staunton; C Drexler; N E Farber |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 88 ISSN: 0003-2999 ISO Abbreviation: Anesth. Analg. Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-03-25 Completed Date: 1999-03-25 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 625-32 Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology, The Medical College of Wisconsin, Milwaukee 53226, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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pharmacokinetics,
pharmacology* Anesthetics, Inhalation / pharmacokinetics, pharmacology* Animals Blood Pressure / drug effects Brain / drug effects*, physiology* Cats Drug Combinations Electroencephalography / drug effects Female Halothane / pharmacokinetics, pharmacology* Heart Rate / drug effects Imidazoles / pharmacokinetics, pharmacology* Male Medetomidine Pulmonary Alveoli / metabolism |
| Grant Support | |
ID/Acronym/Agency:
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R01 GM56398-01/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 0/Anesthetics, Inhalation; 0/Drug Combinations; 0/Imidazoles; 151-67-7/Halothane; 86347-14-0/Medetomidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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