Document Detail

Pretreatment with dexmedetomidine: altered indices of anesthetic depth for halothane in the neuraxis of cats.
MedLine Citation:
PMID:  10072018     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: The anesthetic adjuvant dexmedetomidine seems to differentially alter central nervous system-mediated indices of anesthetic action. Lower brainstem or spinal determinants of anesthetic depth (movement and hemodynamic responses) are more attenuated than those of higher brain functions, such as the electroencephalogram.
W T Schmeling; P Ganjoo; M Staunton; C Drexler; N E Farber
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  88     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-03-25     Completed Date:  1999-03-25     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  625-32     Citation Subset:  AIM; IM    
Department of Anesthesiology, The Medical College of Wisconsin, Milwaukee 53226, USA.
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MeSH Terms
Adrenergic alpha-Agonists / pharmacokinetics,  pharmacology*
Anesthetics, Inhalation / pharmacokinetics,  pharmacology*
Blood Pressure / drug effects
Brain / drug effects*,  physiology*
Drug Combinations
Electroencephalography / drug effects
Halothane / pharmacokinetics,  pharmacology*
Heart Rate / drug effects
Imidazoles / pharmacokinetics,  pharmacology*
Pulmonary Alveoli / metabolism
Grant Support
Reg. No./Substance:
0/Adrenergic alpha-Agonists; 0/Anesthetics, Inhalation; 0/Drug Combinations; 0/Imidazoles; 151-67-7/Halothane; 86347-14-0/Medetomidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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