Document Detail


Pretreatment of exercise-induced asthma with sequential inhalations of fenoterol as aerosol and as powder (first of two parts).
MedLine Citation:
PMID:  6360703     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fifteen adult asthmatics participated in a controlled open randomized study to compare the efficacy on exercise-induced asthma of pretreatment with 1 mg fenoterol administered as inhalation powder and from a pressurized aerosol. Both types of treatment were inhalations of 5 single doses of 0.2 mg fenoterol over a period of 10 minutes. A run of 6 minutes was carried out on a treadmill in a climate chamber 30 minutes after the beginning of the pretreatment, at the same time of day on three days. After pretreatment with the pressurized aerosol a fall was seen in peak expiratory flow of 28% (+/- 5%, SEM) and after pretreatment with inhalation powder the fall was 18% (+/- 4%). This is a statistically significant difference (p less than 0.01).
Authors:
A Bundgaard; A Schmidt
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European journal of respiratory diseases. Supplement     Volume:  130     ISSN:  0106-4347     ISO Abbreviation:  Eur J Respir Dis Suppl     Publication Date:  1983  
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2008-02-21    
Medline Journal Info:
Nlm Unique ID:  8010618     Medline TA:  Eur J Respir Dis Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  59-65     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aerosols
Asthma / prevention & control*
Asthma, Exercise-Induced / physiopathology,  prevention & control*
Clinical Trials as Topic
Ethanolamines / administration & dosage*
Female
Fenoterol / administration & dosage*
Humans
Male
Middle Aged
Powders
Random Allocation
Chemical
Reg. No./Substance:
0/Aerosols; 0/Ethanolamines; 0/Powders; 13392-18-2/Fenoterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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