| Pretreatment evaluation of prostate cancer: role of MR imaging and 1H MR spectroscopy. | |
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MedLine Citation:
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PMID: 15486239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Magnetic resonance (MR) imaging and hydrogen 1 MR spectroscopy of the prostate gland are performed during the same examination with a conventional clinical MR unit. Prostate zonal anatomy and prostate cancer are best depicted on multiplanar T2-weighted MR images. MR imaging and 1H MR spectroscopy are not used as an initial diagnostic tool. Their use in tumor detection is reserved for patients with elevated prostate-specific antigen levels in whom previous biopsy results were negative. The use of MR imaging and 1H MR spectroscopy for the evaluation of tumor location, local extent (extracapsular extension and/or seminal vesicle invasion), volume, and aggressiveness is generating strong clinical interest. In staging and treatment planning, MR imaging has been shown to have an incremental value additive to the value of clinical nomograms. Furthermore, anatomic and metabolic mapping of the prostate gland with 1H MR spectroscopy offers the possibility of optimizing treatment planning (watchful waiting, surgery, or radiation therapy [intensity-modulated radiation therapy or brachytherapy]), thus further expanding the role of MR imaging in the achievement of patient-specific, individualized treatment. |
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Authors:
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Filip G Claus; Hedvig Hricak; Robert R Hattery |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Radiographics : a review publication of the Radiological Society of North America, Inc Volume: 24 Suppl 1 ISSN: 1527-1323 ISO Abbreviation: Radiographics Publication Date: 2004 Oct |
Date Detail:
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Created Date: 2004-10-15 Completed Date: 2005-11-08 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8302501 Medline TA: Radiographics Country: United States |
Other Details:
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Languages: eng Pagination: S167-80 Citation Subset: IM |
Copyright Information:
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Copyright RSNA, 2004 |
Affiliation:
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Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, C278, New York, NY 10021, USA. clausf@mskcc.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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diagnosis*,
therapy Aged Humans Magnetic Resonance Imaging* Magnetic Resonance Spectroscopy* Male Middle Aged Neoplasm Staging Prostate / anatomy & histology Prostatic Neoplasms / diagnosis*, therapy |
| Grant Support | |
ID/Acronym/Agency:
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R01 CA76423/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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