| Preterm labour. Cervical function and prematurity. | |
| | |
MedLine Citation:
|
PMID: 17490914 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The cervix maintains the fetus in situ during pregnancy and dilates during labour to allow delivery of the baby. Congenital or iatrogenically-induced structural abnormalities of the cervix are associated with an increased risk of preterm birth. The role of cervical infection is less clear. Cervical studies may be useful in the prediction of preterm delivery: both a shortened cervical length identified on transvaginal ultrasound examination and an increased level of fetal fibronectin in cervico-vaginal secretions are associated with an increased risk of preterm delivery. In singleton pregnancy, cervical cerclage reduces the risk of preterm birth by 25%. There is no evidence of a reduction in neonatal mortality or morbidity, and the beneficial effects of preterm birth reduction have to be set against the increased risk of maternal infection. Neither the American College of Obstetricians and Gynecologists (ACOG) nor the Royal College of Obstetricians and Gynaecologists (RCOG) has unequivocally endorsed cervical cerclage. Further work is required to define the role of the cervix in prediction and prevention of spontaneous preterm birth. |
| | |
Authors:
|
Jane E Norman |
Related Documents
:
|
1351004 - Sonographic assessment of the incompetent cervix in pregnancy. 10343934 - Changes in the cervical extracellular matrix during pregnancy and parturition. 16271574 - Cervical radiculopathy caused by neural foraminal migration of a herniated calcified in... 16879994 - Up-regulation of the endothelin receptor a in placental tissue from first trimester del... 2532254 - Fertilization and ovum recovery rates in superovulated ewes following cervical insemina... 412514 - Amniotic fluid insulin and glucagon in normal pregnancy and pregnancy complicated by rh... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2007-05-08 |
Journal Detail:
|
Title: Best practice & research. Clinical obstetrics & gynaecology Volume: 21 ISSN: 1521-6934 ISO Abbreviation: Best Pract Res Clin Obstet Gynaecol Publication Date: 2007 Oct |
Date Detail:
|
Created Date: 2007-10-16 Completed Date: 2008-04-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101121582 Medline TA: Best Pract Res Clin Obstet Gynaecol Country: England |
Other Details:
|
Languages: eng Pagination: 791-806 Citation Subset: IM |
Affiliation:
|
University of Glasgow, Division of Developmental Medicine, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, Scotland, UK. j.e.norman@clinmed.gla.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bacterial Infections
/
complications Cerclage, Cervical / methods Cervical Ripening Cervix Uteri / anatomy & histology*, physiology Female Humans Obstetric Labor, Premature / diagnosis, etiology, prevention & control* Pregnancy Pregnancy Complications, Infectious / immunology Uterine Cervical Incompetence / diagnosis, therapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Second-generation endometrial ablation treatment: Novasure.
Next Document: Genetics of preterm labour.