Document Detail


Preterm labor.
MedLine Citation:
PMID:  20148502     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Preventing preterm delivery remains one of the great challenges in modern medicine. Preterm birth rates continue to increase and accounted for 12.7 percent of all U.S. births in 2005. The etiology of preterm delivery is unclear, but is likely to be complex and influenced by genetics and environmental factors. Women with previous preterm birth are at increased risk of subsequent preterm delivery and may be candidates for treatment with antenatal progesterone. Fetal fibronectin testing and endovaginal ultrasonography for cervical length are useful for triage. For the patient in preterm labor, only antenatal corticosteroids and delivery in a facility with a level III neonatal intensive care unit have been shown to improve outcomes consistently. Tocolytic agents may delay delivery for up to 48 hours, enabling the administration of antenatal corticosteroids or maternal transfer. Routine use of antibiotics in preterm labor is not indicated except for group B streptococcus prophylaxis or treatment of chorioamnionitis.
Authors:
William G Sayres
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American family physician     Volume:  81     ISSN:  1532-0650     ISO Abbreviation:  Am Fam Physician     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-12     Completed Date:  2010-04-01     Revised Date:  2010-12-15    
Medline Journal Info:
Nlm Unique ID:  1272646     Medline TA:  Am Fam Physician     Country:  United States    
Other Details:
Languages:  eng     Pagination:  477-84     Citation Subset:  AIM; IM    
Affiliation:
Group Health Cooperative, Spokane, WA 99201, USA. sayres.w@ghc.org
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / administration & dosage
Antihypertensive Agents / administration & dosage
Calcium Channel Blockers / administration & dosage
Female
Humans
Obstetric Labor, Premature / diagnosis,  drug therapy,  epidemiology,  prevention & control*
Pregnancy
Risk Factors
Tocolytic Agents / administration & dosage
Ultrasonography, Prenatal
United States / epidemiology
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Antihypertensive Agents; 0/Calcium Channel Blockers; 0/Tocolytic Agents
Comments/Corrections
Comment In:
Am Fam Physician. 2010 Dec 1;82(11):1310-1; author reply 1312   [PMID:  21121512 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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