Document Detail

Preterm delivery in IVF versus ICSI singleton pregnancies: a national population-based cohort.
MedLine Citation:
PMID:  20880626     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVES: To assess the risk of spontaneous and iatrogenic preterm delivery in singleton pregnancies when comparing in vitro fertilization (IVF) pregnancies with intracytoplasmic sperm injection (ICSI) pregnancies.
STUDY DESIGN: A national population-based cohort study using Norwegian Medical Birth Register data during 1999 through 2006 was designed. The cohort included 5824 singleton pregnancies after IVF and ICSI treatment. Multinomial logistic regression analyses were used to calculate risk estimates.
RESULTS: There were no differences in maternal complicating factors such as pre-eclampsia, hypertension and diabetes between the IVF and ICSI pregnancies. However, IVF pregnancies had a 60% increased risk of moderately (32(+)(0)(days)-36(+)(6)(days) gestational weeks) iatrogenic preterm delivery (OR: 1.6, 95%CI: 1.1-2.2) and a 40% increased risk of iatrogenic preterm delivery <37 weeks (OR: 1.4, 95%CI: 1.02-1.9) compared to ICSI pregnancies.
CONCLUSION: IVF pregnancies were at increased risk of moderately iatrogenic preterm delivery when compared to ICSI pregnancies.
Nils-Halvdan Morken
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Publication Detail:
Type:  Journal Article     Date:  2010-09-29
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  154     ISSN:  1872-7654     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-02-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  62-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Department of Obstetrics and Gynecology, Haukeland University Hospital, 5021 Bergen, Norway.
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