| Preterm birth prevention: evaluation of a prospective controlled randomized trial. | |
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MedLine Citation:
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PMID: 2658606 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Over a 3-year period 5457 indigent patients were scored for risk of preterm birth and 4595 women were delivered at greater than or equal to 20 weeks' gestation. Patients at high risk (18.1%) were randomized into control and intervention groups. The latter group received weekly cervical examinations and instruction regarding subtle symptoms and signs of preterm labor. Medical providers received similar instruction. There was no difference in preterm births between control and intervention groups (20.8% vs. 22.1%). Medical providers, convinced of preterm birth prevention during year 1 of the study, defeated the study design by giving preterm birth precautions to all patients. In turn, preterm births decreased from 13.7% (year 1) to 9.3% (year 2, p less than 0.001) and remained stable in year 3 (8.7%). Preterm births during year 1 and the 8 months preceding year 1 were not different. Significant differences in preterm births between private and indigent study patients during these two periods (p less than 0.001) disappeared during years 2 and 3 of the study. |
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Authors:
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E Mueller-Heubach; D Reddick; B Barnett; R Bente |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 160 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1989 May |
Date Detail:
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Created Date: 1989-06-27 Completed Date: 1989-06-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1172-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Magee-Womens Hospital, PA 15213. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Trials as Topic Female Fetal Membranes, Premature Rupture / epidemiology, prevention & control* Humans Infant Mortality Infant, Newborn Infant, Premature Medical Indigency Obstetric Labor, Premature / epidemiology, prevention & control* Pennsylvania Pregnancy Program Evaluation Prospective Studies Random Allocation Risk Factors |
| Comments/Corrections | |
Comment In:
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Am J Obstet Gynecol. 1990 Jun;162(6):1626-7
[PMID:
2193521
]
Am J Obstet Gynecol. 1990 Jun;162(6):1627-8 [PMID: 2360596 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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