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Preterm PROM: Prediction, Prevention, Principles.
MedLine Citation:
PMID:  21508700     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Preterm premature rupture of the membranes remains difficult to predict accurately. The majority of those suffering preterm premature rupture of the membrane lack risk factors that might lead to preventative treatments. Its management is centered on an evaluation of the risks and benefits of attempted pregnancy prolongation compared with expeditious delivery. An understanding of the gestational age specific risks for newborn morbidity and mortality is essential to estimate the potential benefits of conservative management. Once the diagnosis of membrane rupture remote from term is made, conservative management to reduce neonatal complications is generally attempted while maintaining vigilance for complications such as infection, umbilical cord compression, or abruption. Concurrent antibiotic therapy and antenatal corticosteroid treatment are typically administered to prolong pregnancy, prevent infection, and reduce gestational age dependent morbidities. Near and at term, particularly if fetal pulmonary maturity has been confirmed, the patient is generally best served by expeditious delivery.
Authors:
Thaddeus P Waters; Brian Mercer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  54     ISSN:  1532-5520     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-04-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  307-12     Citation Subset:  IM    
Affiliation:
MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio.
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