| Preterm PROM: Prediction, Prevention, Principles. | |
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MedLine Citation:
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PMID: 21508700 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Preterm premature rupture of the membranes remains difficult to predict accurately. The majority of those suffering preterm premature rupture of the membrane lack risk factors that might lead to preventative treatments. Its management is centered on an evaluation of the risks and benefits of attempted pregnancy prolongation compared with expeditious delivery. An understanding of the gestational age specific risks for newborn morbidity and mortality is essential to estimate the potential benefits of conservative management. Once the diagnosis of membrane rupture remote from term is made, conservative management to reduce neonatal complications is generally attempted while maintaining vigilance for complications such as infection, umbilical cord compression, or abruption. Concurrent antibiotic therapy and antenatal corticosteroid treatment are typically administered to prolong pregnancy, prevent infection, and reduce gestational age dependent morbidities. Near and at term, particularly if fetal pulmonary maturity has been confirmed, the patient is generally best served by expeditious delivery. |
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Authors:
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Thaddeus P Waters; Brian Mercer |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical obstetrics and gynecology Volume: 54 ISSN: 1532-5520 ISO Abbreviation: Clin Obstet Gynecol Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-04-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0070014 Medline TA: Clin Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 307-12 Citation Subset: IM |
Affiliation:
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MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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