Document Detail


Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis.
MedLine Citation:
PMID:  23014355     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hydrogen sulfide is an environmental toxicant and gaseous neurotransmitter. It is produced enterically by sulfur-reducing bacteria and invasive pathogens including Streptococcus anginosus group, Salmonella and Citrobacter. We describe putative focal hydrogen sulfide neurotoxicity after Streptococcus constellatus meningitis, treated with adjunctive sodium nitrite and hyperbaric oxygen therapy.
Authors:
Sumit Verma; Rachel Landisch; Brendan Quirk; Kathleen Schmainda; Melissa Prah; Harry T Whelan; Rodney E Willoughby
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  32     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-18     Completed Date:  2013-10-21     Revised Date:  2014-04-07    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  189-91     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Brain / metabolism,  microbiology
Child, Preschool
Cognition Disorders / chemically induced
Dipyridamole / therapeutic use
Humans
Hydrogen Sulfide / metabolism*
Hyperbaric Oxygenation
Male
Meningitis, Bacterial / metabolism*,  microbiology*
Nervous System Diseases / chemically induced
Sodium Nitrite
Streptococcal Infections / metabolism*,  microbiology*
Streptococcus anginosus / isolation & purification,  metabolism*
Grant Support
ID/Acronym/Agency:
R01 AI093369/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
64ALC7F90C/Dipyridamole; M0KG633D4F/Sodium Nitrite; YY9FVM7NSN/Hydrogen Sulfide
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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