Document Detail

Pressurized bag pump and syringe pump arterial flushing systems: an unrecognized hazard in neonates?
MedLine Citation:
PMID:  12415454     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Hand-held flushing of radial arterial lines at 0.5 ml/s in neonates can result in retrograde embolization of flush solution into the central arterial circulation. We studied flush flow velocities during intermittent arterial line purging using a flow regulating device with an infusion bag pump and a syringe pump system. MEASUREMENTS AND INTERVENTIONS: In this in vitro experiment we simulated flushing of a 24- and a 22-G cannula against a mean arterial pressure of 45 mmHg. Fluid flow velocities were gravimetrically measured during flushing from an infusion bag system pressurized to 100, 200, and 300 mmHg and from a syringe pump flush system after initialization of boluses of 0.5, 1.0, 1.5, 2.0, and 2.5 ml. The flow regulating device was opened for 1, 2, and 5 s. RESULTS: Both flush systems tested allowed delivery of flush flow velocities exceeding 0.5 ml/s (e.g., 22-G cannula; bag system, pressure 300 mmHg up to 0.64+/-0.08 ml/s; syringe pump, 2 ml bolus up to 0.74+/-0.05 ml/s). In syringe pump systems the main determinant of flow velocity was bolus size, in bag pump systems flushing time and bag pressure. CONCLUSIONS: Based on data about critical flow velocities through an radial arterial cannula in neonates, both tested flushing systems carry the risk of exceeding the critical value of 0.5 ml/s. They are likely to cause retrograde embolization of flushing solution into the central arterial circulation with the associated risk of clot and air embolization. In vivo studies should identify margins of safety to minimize the risk of retrograde flushing into the central arterial circulation.
A Cornelius; J Fischer; B Frey; O Baenziger; A Gerber; M Weiss
Related Documents :
16793104 - A miniature ultransonic pump using a bending disk transducer and a gap.
19624584 - Development of a closed air loop electropneumatic actuator for driving a pneumatic bloo...
17938774 - Right ventricular assistance by continuous flow device. a numerical simulation.
18545074 - Acute haemodynamic effects of intra-aortic balloon pump and cardiac resynchronization t...
16002934 - Influence of different trigger techniques on twitch mouth pressure during bilateral ant...
10898424 - Pulse pressure and risk for myocardial infarction and heart failure in the elderly.
Publication Detail:
Type:  In Vitro; Journal Article     Date:  2002-10-04
Journal Detail:
Title:  Intensive care medicine     Volume:  28     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-11-04     Completed Date:  2003-05-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1638-43     Citation Subset:  IM    
Department of Anesthesia, University Children's Hospital Zurich, Steinwiesstrasse 75 8032 Zurich, Switzerland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Catheters, Indwelling*
Embolism / prevention & control*
Equipment Design
Infant, Newborn
Infusion Pumps*
Infusions, Intravenous
Linear Models
Radial Artery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Life-threatening hemorrhage in neonates: management with recombinant activated factor VII.
Next Document:  Acute lung injury and acute respiratory distress syndrome at the intensive care unit of a general un...