Document Detail


Pressure waves in the aorta during isolated abdominal belt loading: the magnitude, phasing, and attenuation.
MedLine Citation:
PMID:  21870376     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
While rupture of the aorta is a leading cause of sudden death following motor vehicle crashes, the specific mechanism that causes this injury is not currently well understood. Aortic ruptures occurring in the field are likely due to a complex combination of contributing factors such as acceleration, compression of the chest, and increased pressure within the aorta. The objective of the current study was to investigate one of these factors in more detail than has been done previously; specifically, to investigate the in situ intra-aortic pressure generated during isolated belt loading to the abdomen. Ten juvenile swine were subjected to dynamic belt loads applied to the abdomen. Intraaortic pressure was measured at multiple locations to assess the magnitude and propagation of the resulting blood pressure wave. The greatest average peak pressure (113.6 +/- 43.5 kPa) was measured in the abdominal aorta. Pressures measured in the thoracic aorta and aortic arch were 70 per cent and 50 per cent, respectively, that measured in the abdominal aorta. No macroscopic aortic trauma was observed. To the authors' knowledge the present study is the first one to document the presence, propagation, and attenuation of a transient pressure wave in the aorta generated by abdominal belt loading. The superiorly moving wave is sufficient to generate hydrostatic and intimal shear stress in the aorta, possibly contributing to the hypothesized mechanisms of traumatic aortic rupture.
Authors:
C Arregui-Dalmases; E Del Pozo; S Stacey; M Kindig; D Lessley; F Lopez-Valdes; J Forman; R Kent
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine     Volume:  225     ISSN:  0954-4119     ISO Abbreviation:  Proc Inst Mech Eng H     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-08-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908934     Medline TA:  Proc Inst Mech Eng H     Country:  England    
Other Details:
Languages:  eng     Pagination:  688-95     Citation Subset:  IM    
Affiliation:
European Center for Injury Prevention, Preventive and Public Health Department, University of Navarra, Pamplona, Spain. carlosarregui@unav.es
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