| Pressure-relieving interventions for treating diabetic foot ulcers. | |
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MedLine Citation:
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PMID: 23440787 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Diabetes-related foot ulceration is a major contributor to morbidity in diabetes. Diabetic foot ulcers are partly a consequence of abnormal foot pressures and pressure relief is a widely used treatment for healing diabetes-related plantar foot ulcers, but the most effective method for healing is unclear. OBJECTIVES: To determine the effects of pressure-relieving interventions on the healing of foot ulcers in people with diabetes. SEARCH METHODS: For this update we searched the Cochrane Wounds Group Specialised Register (searched 2 November 2012); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 10); Ovid MEDLINE (1950 to October Week 4 2012); Ovid MEDLINE (In-Process & Other Non-Indexed Citations, October 31, 2012); Ovid EMBASE (1980 to 2012 Week 43); and EBSCO CINAHL (1982 to 1 November 2012). There were no restrictions based on language or publication status. SELECTION CRITERIA: Randomised controlled trials evaluating the effects of pressure-relieving interventions on the healing of foot ulcers in people with diabetes. DATA COLLECTION AND ANALYSIS: Data from eligible trials were extracted, and summarised using a data extraction sheet, by two review authors independently. MAIN RESULTS: Fourteen trials (709 participants) met the inclusion criteria for the review. One study compared two different types of non-removable casts with no discernable difference between the groups. Seven studies (366 participants) compared non-removable casts with removable pressure-relieving devices. In five of those studies non-removable casts were associated with a statistically significant increase in the number of ulcers healed compared with the removable device (RR 1.17 95% CI 1.01 to 1.36: P value = 0.04).Two studies (98 participants) found that significantly more ulcers healed with non-removable casts than with dressings alone. Achilles tendon lengthening combined with a non-removable cast in one study resulted in significantly more healed ulcers at 7 months than non-removable cast alone (RR 2.23; 95% CI 1.32 to 3.76). More ulcers remained healed at two years in this group (RR 3.41; 95% CI 1.42 to 8.18).Other comparisons included surgical debridement of ulcers; felt fitted to the foot; felted foam dressings and none of these showed a statistically significant treatment effect in favour of the intervention. AUTHORS' CONCLUSIONS: Non-removable, pressure-relieving casts are more effective in healing diabetes related plantar foot ulcers than removable casts, or dressings alone. Non-removable devices, when combined with Achilles tendon lengthening were more successful in one forefoot ulcer study than the use of a non-removable cast alone. |
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Authors:
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Jane Lewis; Allyson Lipp |
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Publication Detail:
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Type: Journal Article Date: 2013-01-31 |
Journal Detail:
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Title: Cochrane database of systematic reviews (Online) Volume: 1 ISSN: 1469-493X ISO Abbreviation: Cochrane Database Syst Rev Publication Date: 2013 |
Date Detail:
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Created Date: 2013-02-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100909747 Medline TA: Cochrane Database Syst Rev Country: England |
Other Details:
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Languages: eng Pagination: CD002302 Citation Subset: IM |
Affiliation:
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Cardiff and Vale University Health Board, Cardiff, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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