Document Detail


Pressure overload.
MedLine Citation:
PMID:  22108724     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This review discusses cardiac consequences of pressure overload. In response to elevated pressure, the ventricular hypertrophy compensates for the increased wall stress. However, the ventricular hypertrophy involves numerous structural adaptations that may lead to ventricular dysfunction and, eventually, heart failure. Particular emphasis is placed on molecular mechanisms that govern the development of hypertrophy and that may lead to maladaptive structural changes resulting in adverse cardiac events.
Authors:
Edward D Frohlich; Dinko Susic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart failure clinics     Volume:  8     ISSN:  1551-7136     ISO Abbreviation:  Heart Fail Clin     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-11-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231934     Medline TA:  Heart Fail Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  21-32     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Hypertension Research Laboratory, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA.
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