| Pressure-induced apoptosis in human lymphoblasts. | |
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MedLine Citation:
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PMID: 9281364 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The viability of human lymphoblasts was investigated after compression at 37 degrees C for 30 min. Immediately after decompression, necrotic cells were observed and the viability decreased sigmoidally to 0 with increasing pressure from 85 to 200 MPa. Apoptotic cells began to be observed from 8 h after decompression in the case of compression at 100 MPa for 30 min at 37 degrees C. The apoptosis was confirmed to be pressure-induced by the Tunel method and by optical and electron microscopy. Cell death by both necrosis and apoptosis due to compression was accelerated in the S phase of the cell cycle. |
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Authors:
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K J Takano; T Takano; Y Yamanouchi; T Satou |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Experimental cell research Volume: 235 ISSN: 0014-4827 ISO Abbreviation: Exp. Cell Res. Publication Date: 1997 Aug |
Date Detail:
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Created Date: 1997-09-30 Completed Date: 1997-09-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0373226 Medline TA: Exp Cell Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 155-60 Citation Subset: IM |
Affiliation:
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Institute of Materials Science, University of Tsukuba, Tsukuba, Japan. takano@mat.ims.tsukuba.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Apoptosis* Cell Survival Cells, Cultured Chromatin / ultrastructure DNA / biosynthesis DNA Fragmentation Humans Kinetics Lymphocytes / cytology*, physiology*, ultrastructure Male Microscopy, Electron Necrosis Nuclear Envelope / ultrastructure Pressure Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Chromatin; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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