Document Detail

Pressure (decubitus) ulcer: variation in histopathology--a light and electron microscope study.
MedLine Citation:
PMID:  7860049     Owner:  NLM     Status:  MEDLINE    
The histopathology of pressure (decubitus) ulcers from 20 patients was examined by light and electron microscopy. Surgical biopsy specimens from the ulcer edge, ulcer margin, and adjacent normal, nonulcerated skin showed four general types of ulcer histopathology. Morphological features common to all ulcer groups were a dense fibrin matrix, occluded blood vessels, numerous inflammatory cells, and a range of cellular viability from functionally normal appearing cells to cells in all stages of necrosis. These data present structural reference points for comparing pressure ulcer pathology and evaluating the effects of growth factors on wound healing.
J S Vande Berg; R Rudolph
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Human pathology     Volume:  26     ISSN:  0046-8177     ISO Abbreviation:  Hum. Pathol.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-03-23     Completed Date:  1995-03-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  195-200     Citation Subset:  IM    
San Diego Veterans Administration Medical Center, CA 92161.
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MeSH Terms
Pressure Ulcer / pathology*
Skin / pathology,  ultrastructure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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