| Pressure-based simultaneous CFR and FFR measurements: understanding the physiology of a stenosed vessel. | |
| | |
MedLine Citation:
|
PMID: 11535201 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Arterial stenosis is known to be one of the most serious cardiovascular diseases. Angiographical estimation of arterial stenosis provides limited information on the severity of the occlusion and the flow of blood through it. Hemodynamical assessment of the flow and pressure behaviour, is known to be clinically important. Hemodynamically based parameters, such as pressure based myocardial fractional flow reserve (FFR) and the flow based coronary flow reserved (CFR) were introduced to provide a much better tool for treating arterial diseases. We have developed a new method for simultaneous measurement of pressure-derived CFR and FFR. The advantage of pressure derived hemodynamic parameters is very substantial, and its relatively straightforward application in clinical setting is solid. The method has been validated by means of a computational fluid dynamics (CFD) model of the arterial stenosis and in vitro bench studies. |
| | |
Authors:
|
E Shalman; C Barak; E Dgany; H Noskowitcz; S Einav; M Rosenfeld |
Publication Detail:
|
Type: In Vitro; Journal Article |
Journal Detail:
|
Title: Computers in biology and medicine Volume: 31 ISSN: 0010-4825 ISO Abbreviation: Comput. Biol. Med. Publication Date: 2001 Sep |
Date Detail:
|
Created Date: 2001-09-05 Completed Date: 2001-10-11 Revised Date: 2009-11-03 |
Medline Journal Info:
|
Nlm Unique ID: 1250250 Medline TA: Comput Biol Med Country: United States |
Other Details:
|
Languages: eng Pagination: 353-63 Citation Subset: IM |
Affiliation:
|
Florence Medical Ltd., Sharona Center, 12 Derech Hasharon, Kfar Saba, Israel. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Algorithms Arterial Occlusive Diseases / physiopathology* Arteries / physiopathology Blood Pressure / physiology Computer Simulation* Constriction, Pathologic Coronary Circulation / physiology* Hemodynamics / physiology Humans Models, Cardiovascular* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Virtual reality orthopedic surgery simulator.
Next Document: Computational particle-hemodynamics analysis and geometric reconstruction after carotid endarterecto...