Document Detail

Pressure controlled clamp using shape memory alloy for minimal vessel invasion in blood flow occlusion.
MedLine Citation:
PMID:  22785453     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Vessel damage after clamping may affect the success of surgical operations. A new pressure controlled clamp (SMA clamp) was designed using super elastic property of shape memory alloy (SMA) to realize atraumatic vessel occlusion. The ability and biological effect of the SMA clamp to control pressure was investigated in vivo.
METHODS: The loading-displacement curves of the SMA clamps (experimental group) and conventional clamp (control group) by occlusion of pig carotid arteries were evaluated using a clamping-pressure analyzing system. To investigate macroscopically and histologically the vessel damage of the SMA and conventional clamps, pig carotid arteries were stained with Evan's blue and its histological sections were stained with Elastica Massion after clamping for fifteen minutes.
RESULTS: Constant value was shown in the loading-displacement curve of SMA clamp. In the control group, damaged area stained with Evan's blue in the vessel wall showed enlargement with the pressure increasing. Less areas in experimental groups are observed than that in the control group. Histological section in the experimental group showed no obvious except a slight compressive damage in the tunica intima. In the control group, vessel wall showed irreversible damages.
CONCLUSIONS: This experiment indicated that the SMA clamp, which has a unique mechanical property, can be used without vessels damage. This pressure controlled clamp can be a selection in clinical apparatus to improve surgical safety.
Ye Zhang; Hiroyasu Kanetaka; Yuya Sano; Mitsuhiro Kano; Tadaaki Kudo; Takumi Sato; Yoshinaka Shimizu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-06-15
Journal Detail:
Title:  Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia     Volume:  19     ISSN:  2186-1005     ISO Abbreviation:  Ann Thorac Cardiovasc Surg     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-04-08     Completed Date:  2013-10-22     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  9703158     Medline TA:  Ann Thorac Cardiovasc Surg     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  35-42     Citation Subset:  IM    
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MeSH Terms
Carotid Arteries / pathology,  physiopathology,  surgery*
Carotid Artery Injuries / etiology,  pathology,  prevention & control*
Equipment Design
Materials Testing
Models, Animal
Regional Blood Flow
Surgical Instruments*
Vascular Surgical Procedures / adverse effects,  instrumentation*
Vascular System Injuries / etiology,  pathology,  prevention & control*
Reg. No./Substance:
12035-60-8/titanium nickelide; 7OV03QG267/Nickel; D1JT611TNE/Titanium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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