| Preserved oscillatory response but lack of mismatch negativity in patients with disorders of consciousness. | |
| | |
MedLine Citation:
|
PMID: 21377413 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVE: The diagnostic validity of non-phase-locked oscillations (NPLOs) and mismatch negativity (MMN) in an oddball task for assessing attentional reactivity in patients with disordered consciousness was examined. METHODS: Patients in a minimally conscious (MCS, n=6) or vegetative (VS, n=16) state and healthy controls (n=15) were assessed. MMN and NPLOs were analyzed with single-subject, non-parametric statistics. RESULTS: In 11 healthy controls and 2 VS patients, MMN was detected. More subjects showed NPLO differences in the alpha than in the theta or beta frequency ranges. In 14 healthy controls, 4 MCS patients, and 5 VS patients, lower amplitudes after deviants were found in the alpha frequency range. One healthy subject and one VS patient showed higher amplitudes after deviants. CONCLUSIONS: Neither ERPs nor NPLOs could reliably distinguish MCS from VS patients. However, NPLOs were more sensitive than ERPs for detecting significantly different activity, and they possibly identified preserved processing better than ERPs. SIGNIFICANCE: Intact neurophysiological attentional responses observed in the NPLOs of VS patients may indicate a need for other diagnostic techniques. Inter-individual differences in the direction of the effect should be considered as normal variance. |
| | |
Authors:
|
Yvonne Höller; Jürgen Bergmann; Martin Kronbichler; Julia Sophia Crone; Elisabeth Verena Schmid; Stefan Golaszewski; Gunther Ladurner |
Related Documents
:
|
21768433 - Gastroesophageal reflux disease symptom severity, proton pump inhibitor use, and esopha... 11790163 - Amyopathic dermatomyositis: a review by the italian group of immunodermatology. 10918893 - Long-term domiciliary oxygen therapy--the johannesburg hospital experience. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-3 |
Journal Detail:
|
Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: - ISSN: 1872-8952 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-7 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Psychology and Center for Neurocognitive Research, University of Salzburg, Austria; Neuroscience Institute and Center for Neurocognitive Research, Christian-Doppler-Clinic, Paracelsus Private Medical University, Salzburg, Austria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Distraction task rather than focal attention modulates gamma activity associated with auditory stead...
Next Document: Transcranial direct current stimulation modulates the spinal plasticity induced with patterned elect...